Nanotechnology-empowered vaccine delivery for enhancing CD8+ T cells-mediated cellular immunity

G Liu, M Zhu, X Zhao, G Nie - Advanced drug delivery reviews, 2021 - Elsevier
After centuries of development, using vaccination to stimulate immunity has become an
effective method for prevention and treatment of a variety of diseases including infective …

[HTML][HTML] Vaccination strategies based on bacterial self-assembling proteins as antigen delivery nanoscaffolds

F Lamontagne, V Khatri, P St-Louis, S Bourgault… - Vaccines, 2022 - mdpi.com
Vaccination has saved billions of human lives and has considerably reduced the economic
burden associated with pandemic and endemic infectious diseases. Notwithstanding major …

[HTML][HTML] Chimeric fusion (F) and attachment (G) glycoprotein antigen delivery by mRNA as a candidate Nipah vaccine

RJ Loomis, AT DiPiazza, S Falcone… - Frontiers in …, 2021 - frontiersin.org
Nipah virus (NiV) represents a significant pandemic threat with zoonotic transmission from
bats-to-humans with almost annual regional outbreaks characterized by documented human …

[HTML][HTML] Harnessing the immune system with cancer vaccines: From prevention to therapeutics

I Le, S Dhandayuthapani, J Chacon, AM Eiring… - Vaccines, 2022 - mdpi.com
Prophylactic vaccination against infectious diseases is one of the most successful public
health measures of our lifetime. More recently, therapeutic vaccination against established …

[HTML][HTML] Antigen cross-presentation in dendric cells: From bench to bedside

T Zhang, A Aipire, Y Li, C Guo, J Li - Biomedicine & Pharmacotherapy, 2023 - Elsevier
Cross-presentation (XPT) is an adaptation of the cellular process in which dendritic cells
(DCs) present exogenous antigens on major histocompatibility complex (MHC) class I …

[HTML][HTML] Changes of Host Immunity Mediated by IFN-γ+ CD8+ T Cells in Children with Adenovirus Pneumonia in Different Severity of Illness

R Zheng, Y Li, D Chen, J Su, N Han, H Chen, Z Ning… - Viruses, 2021 - mdpi.com
The host immunity of patients with adenovirus pneumonia in different severity of illness is
unclear. This study compared the routine laboratory tests and the host immunity of human …

[HTML][HTML] T-cell immunity to SARS-CoV-2: what if the known best is not the optimal course for the long run? Adapting to evolving targets

AE Nowill, M Caruso, PO de Campos-Lima - Frontiers in immunology, 2023 - frontiersin.org
Humanity did surprisingly well so far, considering how unprepared it was to respond to the
coronavirus disease 2019 (COVID-19) threat. By blending old and ingenious new …

[HTML][HTML] The macrophage infectivity potentiator of Trypanosoma cruzi induces innate IFN-γ and TNF-α production by human neonatal and adult blood cells through …

S Ait Djebbara, S Mcheik, P Percier, N Segueni… - Frontiers in …, 2023 - frontiersin.org
We previously identified the recombinant (r) macrophage (M) infectivity (I) potentiator (P) of
the protozoan parasite Trypanosoma cruzi (Tc)(rTcMIP) as an immuno-stimulatory protein …

[HTML][HTML] AMDV vaccine: challenges and perspectives

NM Markarian, L Abrahamyan - Viruses, 2021 - mdpi.com
Aleutian mink disease virus (AMDV) is known to cause the most significant disease in the
mink industry. It is globally widespread and manifested as a deadly plasmacytosis and …

[HTML][HTML] Recombinant Protein Vaccines Formulated with Enantio-Specific Cationic Lipid R-DOTAP Induce Protective Cellular and Antibody-Mediated Immune …

SK Gandhapudi, H Shi, MR Ward, JP Bush… - Viruses, 2023 - mdpi.com
Adjuvants are essential components of subunit vaccines added to enhance immune
responses to antigens through immunomodulation. Very few adjuvants have been approved …