Over the past year, numerous studies in the peer reviewed and preprint literature have
reported on the virological, epidemiological and clinical characteristics of the coronavirus …

Although mRNA vaccine efficacy against severe coronavirus disease 2019 remains high,
variant emergence has prompted booster immunizations. However, the effects of repeated …

T cell responses play an important role in protection against beta-coronavirus infections,
including SARS-CoV-2, where they associate with decreased COVID-19 disease severity …

The T cell memory response is a crucial component of adaptive immunity responsible for
limiting or preventing viral reinfection. T cell memory after infection with the SARS-CoV-2 …

Abstract The SARS-CoV-2 Omicron variant has more than 15 mutations in the receptor
binding domain of the Spike protein enabling increased transmissibility and viral escape …

Knowledge of the epitopes of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-
2) targeted by T cells in recovered (convalescent) individuals is important for understanding …

The emergence of SARS-CoV-2 variants of concern (VOC) is driven by mutations that
mediate escape from neutralizing antibodies. There is also evidence that mutations can …

Background COVID-19 patients may experience “cytokine storm” when human immune
system produces excessive cytokines/chemokines. However, it remains unclear whether …

The SARS-CoV-2 pandemic has, as of July 2022, infected more than 550 million people and
caused over 6 million deaths across the world. COVID-19 vaccines were quickly developed …

Objectives To identify individual characteristics associated with serological COVID-19
vaccine responsiveness and the durability of vaccine-induced antibodies. Methods Adults …