The aim of this present study was to evaluate the combination properties between
mucoadhesion/mucus permeability of thiolated chitosans (TC) and their resulting …

The low toxicity and efficient gene delivery of polymeric vectors remain the major barrier to
the clinical application of non-viral gene therapy. Here, we present a poly-d, l-succinimide …

To generate a good carrier for gene transfection, O-carboxymethyl chitosan-graft-branched
polyethylenimine (OCMPEI) copolymers were synthesized by increasing the weight …

Chemical modification and graft copolymerization were commonly adopted to prepare super
absorbent materials. However, physical microstructure of pure chitosan film was optimized to …

The viscous and elastic mucus layer is still an undesirable barrier for oral insulin delivery. To
solve the problem, virus-mimicking nanosized polyelectrolyte complex (PEC) was designed …

Non-steroidal anti-inflammatory drugs (NSAIDS) are emerging as a particularly valuable
class of drugs due to their recently reported anti-tumoral activity in colorectal cancer …

Antimicrobial peptides (AMPs) offer a great promise in designing new therapeutics due to
their ability to interfere in bacterial growth by penetrating the cell wall. The overuse of …

Abstract Platelet-rich fibrin (PRF), derived from human blood, rich in wound healing
components, has drawbacks in direct injections, such as rapid matrix degradation and …

Ketoprofen (KET), commonly used for inflammation in clinical settings, leads to systemic
adverse effects with prolonged use, mitigated by topical administration. Nanotechnology …

In this study, chitosan (CS) grafted by glycidyltrimethylammonium chloride (GTMAC) to form
GTMAC-CS was synthesized, chemically identified, and rheologically characterized. The …