Background & Aims Multiple environmental factors have been associated with the
development of inflammatory bowel diseases (IBDs). We performed an umbrella review of …

The bacterial pathogen Helicobacter pylori has co-evolved with humans and colonizes
approximately 50% of the human population, but only causes overt gastric disease in a …

Objective In this study, we determined whether Helicobacter pylori (H. pylori) infection
dampens the efficacy of cancer immunotherapies. Design Using mouse models, we …

The changing epidemiology of inflammatory bowel disease (IBD) across time and
geography suggests that environmental factors play a major role in modifying disease …

The gastrointestinal microbiota has come to the fore in the search for the causes of IBD. This
shift has largely been driven by the finding of genetic polymorphisms involved in …

Autoimmune diseases are considered as one of the most important disorders of the immune
system, in which the prolonged and chronic processes eliminate self-tolerance to the auto …

This review aimed to summarize the epidemiology (incidence, prevalence and morality) and
risk factors of inflammatory bowel disease (IBD). IBD is a chronic, relapsing, inflammatory …

Inflammatory bowel diseases (IBD), including both Crohn's disease and ulcerative colitis,
are disorders of chronic inflammation of the gastrointestinal tract marked by episodes of …

The UK and China provide unique historical perspectives on the evolution of the incidence
of inflammatory bowel disease, which might provide insight into its pathogenesis. Historical …

Acute and chronic inflammatory diseases of the intestine impart a significant and negative
impact on the health and well-being of human and non-human mammalian animals …