Contemporary studies on aging and longevity have largely overlooked the role that
adaptation plays in lifespan variation across species. Emerging evidence indicates that the …

Autophagy is a fundamental multi-tasking adaptive cellular degradation and recycling
strategy. Following its causal implication in age-related decline, autophagy is currently …

Within primates, the great apes are outliers both in terms of body size and lifespan, since
they include the largest and longest-lived species in the order. Yet, the molecular bases …

The risk of developing cancer is correlated with body size and lifespan within species, but
there is no correlation between cancer and either body size or lifespan between species …

The advent of next generation sequencing technologies (NGS) has greatly accelerated our
understanding of critical aspects of organismal biology from non-model organisms. Bats …

Bats are exceptional among mammals for their powered flight, extended lifespans, and
robust immune systems and therefore have been of particular interest in comparative …

The genetic roots of the diverse paces and shapes of ageing and of the large variations in
longevity observed across the tree of life are poorly understood. Indeed, pathways …

Microcebus murinus, or gray mouse lemur (GML), is one of the smallest primates known,
with a size in between mice and rats. The small size, genetic proximity to humans and …

How, when, and why organisms age are fascinating issues that can only be fully addressed
by adopting an evolutionary perspective. Consistently, the main evolutionary theories of …

How, when, and why do organisms, their tissues, and their cells age remain challenging
issues, although researchers have identified multiple mechanistic causes of aging, and …