Acute chorioamnionitis and funisitis: definition, pathologic features, and clinical significance
Acute inflammatory lesions of the placenta consist of diffuse infiltration of neutrophils at
different sites in the organ. These lesions include acute chorioamnionitis, funisitis, and …
different sites in the organ. These lesions include acute chorioamnionitis, funisitis, and …
The Th1: th2 dichotomy of pregnancy and preterm labour
L Sykes, DA MacIntyre, XJ Yap, TG Teoh… - Mediators of …, 2012 - Wiley Online Library
Pregnancy is a unique immunological state in which a balance of immune tolerance and
suppression is needed to protect the fetus without compromising the mother. It has long …
suppression is needed to protect the fetus without compromising the mother. It has long …
Prevalence and clinical significance of sterile intra‐amniotic inflammation in patients with preterm labor and intact membranes
Problem Inflammation and infection play a major role in preterm birth. The purpose of this
study was to (i) determine the prevalence and clinical significance of sterile intra‐amniotic …
study was to (i) determine the prevalence and clinical significance of sterile intra‐amniotic …
Sterile and microbial-associated intra-amniotic inflammation in preterm prelabor rupture of membranes
Objective: The objectives of this study were to:(1) determine the amniotic fluid (AF)
microbiology of patients with preterm prelabor rupture of membranes (PROM); and (2) …
microbiology of patients with preterm prelabor rupture of membranes (PROM); and (2) …
Inflammasomes: their role in normal and complicated pregnancies
Inflammasomes are cytoplasmic multiprotein complexes that coordinate inflammatory
responses, including those that take place during pregnancy. Inflammasomes and their …
responses, including those that take place during pregnancy. Inflammasomes and their …
Sterile intra-amniotic inflammation in asymptomatic patients with a sonographic short cervix: prevalence and clinical significance
Objective: To determine the frequency and clinical significance of sterile and microbial-
associated intra-amniotic inflammation in asymptomatic patients with a sonographic short …
associated intra-amniotic inflammation in asymptomatic patients with a sonographic short …
A novel molecular microbiologic technique for the rapid diagnosis of microbial invasion of the amniotic cavity and intra‐amniotic infection in preterm labor with intact …
Problem The diagnosis of microbial invasion of the amniotic cavity (MIAC) has been
traditionally performed using traditional cultivation techniques, which require growth of …
traditionally performed using traditional cultivation techniques, which require growth of …
Pathogenesis of preterm labor and preterm premature rupture of membranes associated with intraamniotic infection
A growing body of evidence supports a role for intrauterine infection in preterm labor and
preterm premature rupture of membranes (PROM). This article reviews the definition …
preterm premature rupture of membranes (PROM). This article reviews the definition …
Treatment of abnormal vaginal flora in early pregnancy with clindamycin for the prevention of spontaneous preterm birth: a systematic review and metaanalysis
RF Lamont, CL Nhan-Chang, JD Sobel… - American journal of …, 2011 - Elsevier
The purpose of this study was to determine whether the administration of clindamycin to
women with abnormal vaginal flora at< 22 weeks of gestation reduces the risk of preterm …
women with abnormal vaginal flora at< 22 weeks of gestation reduces the risk of preterm …
Evidence of perturbations of the cytokine network in preterm labor
Objective Intraamniotic inflammation/infection is the only mechanism of disease with
persuasive evidence of causality for spontaneous preterm labor/delivery. Previous studies …
persuasive evidence of causality for spontaneous preterm labor/delivery. Previous studies …