Type VII secretion systems: structure, functions and transport models
A Rivera-Calzada, N Famelis, O Llorca… - Nature Reviews …, 2021 - nature.com
Type VII secretion systems (T7SSs) have a key role in the secretion of effector proteins in
non-pathogenic mycobacteria and pathogenic mycobacteria such as Mycobacterium …
non-pathogenic mycobacteria and pathogenic mycobacteria such as Mycobacterium …
Roles of two-component regulatory systems in antibiotic resistance
ARP Tierney, PN Rather - Future microbiology, 2019 - Taylor & Francis
Two-component regulatory systems (TCSs) are a major mechanism by which bacteria sense
and respond to changes in their environment. TCSs typically consist of two proteins that …
and respond to changes in their environment. TCSs typically consist of two proteins that …
[HTML][HTML] The role of solute binding proteins in signal transduction
The solute binding proteins (SBPs) of prokaryotes are present in the extracytosolic space.
Although their primary function is providing substrates to transporters, SBPs also stimulate …
Although their primary function is providing substrates to transporters, SBPs also stimulate …
Applications of Transcriptomics and Proteomics for Understanding Dormancy and Resuscitation in Mycobacterium tuberculosis
M Kundu, J Basu - Frontiers in Microbiology, 2021 - frontiersin.org
Mycobacterium tuberculosis can survive within its host for extended periods of time without
any clinical symptoms of disease and reactivate when the immune system is weakened. A …
any clinical symptoms of disease and reactivate when the immune system is weakened. A …
An evolutionary paradigm favoring cross talk between bacterial two-component signaling systems
The prevalent paradigm governing bacterial two-component signaling systems (TCSs) is
specificity, wherein the histidine kinase (HK) of a TCS exclusively activates its cognate …
specificity, wherein the histidine kinase (HK) of a TCS exclusively activates its cognate …
Acetylation of Response Regulator Protein MtrA in M. tuberculosis Regulates Its Repressor Activity
MtrA is an essential response regulator (RR) protein in M. tuberculosis, and its activity is
modulated after phosphorylation from its sensor kinase MtrB. Interestingly, many regulatory …
modulated after phosphorylation from its sensor kinase MtrB. Interestingly, many regulatory …
Mycobacterium tuberculosis senses host Interferon-γ via the membrane protein MmpL10
Mycobacterium tuberculosis (Mtb) is one of the most successful human pathogens. Several
cytokines are known to increase virulence of bacterial pathogens, leading us to investigate …
cytokines are known to increase virulence of bacterial pathogens, leading us to investigate …
RegX3 Activates whiB3 Under Acid Stress and Subverts Lysosomal Trafficking of Mycobacterium tuberculosis in a WhiB3-Dependent Manner
AC Mahatha, S Mal, D Majumder, S Saha… - Frontiers in …, 2020 - frontiersin.org
Two-component systems (TCSs) are central to the ability of Mycobacterium tuberculosis to
respond to stress. One such paired TCS is SenX3-RegX3, which responds to phosphate …
respond to stress. One such paired TCS is SenX3-RegX3, which responds to phosphate …
Nitrate-nitrite fate and oxygen sensing in dormant Mycobacterium tuberculosis: A bioinorganic approach highlighting the importance of transition metals
Mycobacterium tuberculosis (Mtb), the agent of tuberculosis (TB), is able to adapt to
unfavorable environments within the human host. The World Health Organization (WHO) …
unfavorable environments within the human host. The World Health Organization (WHO) …
Role of two‐component regulatory systems in intracellular survival of Mycobacterium tuberculosis
X Li, X Lv, Y Lin, J Zhen, C Ruan… - Journal of cellular …, 2019 - Wiley Online Library
The typical two‐component regulatory systems (TCSs), consisting of response regulator and
histidine kinase, play a central role in survival of pathogenic bacteria under stress conditions …
histidine kinase, play a central role in survival of pathogenic bacteria under stress conditions …