Clinical datasets are kept in diverse and disparate formats that are specific to systems these
datasets are created in and might not be related to any known clinical data modelling …

ONTRACANCRUM [1-2] is developing a composite multilevel platform for simulating
malignant tumor development and tumor and normal tissue response to therapeutic …

Cancer Informatics represents a hybrid discipline encompassing the fields of oncology,
computer science, bioinformatics, statistics, computational biology, genomics, proteomics …

Simulators of tumour growth can estimate the evolution of tumour volume and the quantity of
various categories of cells as functions of time. However, the execution time of each …

Title: Computer Modeling of Tissue Development Author: Vojtech Bednaf Department:
Department of Applied Mathematics Supervisor: Doc. RNDr. Zdenek Hedrlm, CSc. Abstract …

Computer simulation is finding a role in an increasing number of scientific disciplines,
concomitant with the rise in available computing power. Realizing this inevitably re-quires …

The challenge of modelling cancer presents a major opportunity to improve our ability to
reduce mortality from malignant neoplasms, improve treatments and meet the demands …

Abstract 4th-grade glioma (Glioblastoma multiforme) is the most aggressive type of brain
cancer. Several mathematical models have been developed towards identifying the …

The crucial role of imaging biomarkers is sparsely mentioned in the literature due to the
complex nature of medical images, the interpretation variability and the multidisciplinary …

The aim of this paper is to present the basics of the discrete event/discrete entity based
modeling approach developed by the In Silico Oncology Group, National Technical …