Background: Individuals with major depressive disorder (MDD) and a lifetime history of
attempted suicide demonstrate lower antidepressant response rates than those without a …

Clinical epidemiological studies have found high co-occurrence between suicide attempts
(SA) and opioid use disorder (OUD). However, the patterns of correlation and causation …

Introduction Few, if any, prior studies have considered whether undetermined intent (UDI)
deaths and suicide deaths differ with respect to genetic liability for suicidal behavior or …

Background Previous studies have demonstrated substantial associations between
substance use disorders (SUD) and suicidal behavior. The current study empirically …

Background Adolescent suicide is a major health problem in the US marked by a recent
increase in risk of suicidal behavior among Black/African American youth. While genetic …

Some personality traits, especially neuroticism, has been found to be associated with
suicide attempt (SA) in mood disorder patients. The present study explored the association …

Ketamine, a racemic mixture of esketamine (S-ketamine) and arketamine (R-ketamine), has
received particular attention for its rapid antidepressant and antisuicidal effects. NMDA …

Importance Many psychiatric outcomes share a common etiologic pathway reflecting
behavioral disinhibition, generally referred to as externalizing (EXT) disorders. Recent …

Background Both fatal and nonfatal suicidal behaviours are important complications of
mental, neurological, and substance use disorders (MNSDs) worldwide. We aimed at …

Depression is a common and complex psychiatric illness with considerable heritability.
Genome-wide association studies (GWAS) have been conducted among different definitions …