Genome‐wide association studies: utility and limitations for research in physiology

N Pereira Ciochetti, B Lugli‐Moraes… - The Journal of …, 2023 - Wiley Online Library
Physiological systems are subject to interindividual variation encoded by genetics. Genome‐
wide association studies (GWAS) operate by surveying thousands of genetic variants from a …

Exposure to alcohol outlets and risk of suicidal behavior in a Swedish cohort of young adults

AC Edwards, H Ohlsson, S Lannoy… - Alcohol: Clinical and …, 2023 - Wiley Online Library
Background Greater alcohol accessibility, for example in the form of a high density of alcohol
outlets or low alcohol taxation rates, may be associated with increased risk of suicidal …

Completed suicide is associated with a higher polygenic burden for psychiatric disorders

M Mitjans, S Papiol, C Barrot… - European archives of …, 2022 - Springer
Suicide is one of the most relevant public health concerns nowadays, involving
approximately 1 million annual deaths worldwide. According to World Health Organization …

Psychiatric comorbidities in epilepsy: population co-occurrence, genetic correlations and causal effects

VH Ahlqvist, C Dardani, P Madley-Dowd… - General …, 2024 - discovery.ucl.ac.uk
Background: Psychiatric comorbidities are common in patients with epilepsy. Reasons for
the co-occurrence of psychiatric conditions and epilepsy remain poorly understood. Aim: We …

Functional and molecular characterization of suicidality factors using phenotypic and genome-wide data

A Quintero Reis, BA Newton, R Kessler… - Molecular …, 2023 - nature.com
Genome-wide association studies (GWAS) of suicidal thoughts and behaviors support the
existence of genetic contributions. Continuous measures of psychiatric disorder symptom …

[HTML][HTML] Examining Differences in the Genetic and Functional Architecture of Attention-Deficit/Hyperactivity Disorder Diagnosed in Childhood and Adulthood

S Breunig, JM Lawrence, IF Foote, HJ Gebhardt… - … Psychiatry Global Open …, 2024 - Elsevier
Background Attention-deficit/hyperactivity disorder (ADHD) is a neurodevelopmental
disorder with diagnostic criteria requiring symptoms to begin in childhood. We investigated …

Omics approaches to investigate the pathogenesis of suicide

M Boldrini, Y Xiao, T Sing, C Zhu, M Jabbi… - Biological …, 2024 - Elsevier
Suicide is the second leading cause of death in US adolescents and young adults, and
generally associated with a psychiatric disorder. Suicidal behavior has a complex etiology …

Impact of COVID-19 on acute care hospitalizations for suicidality

A Dellazoppa, K Porada, JA Zaspel… - Hospital …, 2024 - publications.aap.org
BACKGROUND AND OBJECTIVES The coronavirus disease 2019 (COVID-19) pandemic
contributed to the public health crisis for pediatric mental health. We characterized our local …

Scrutinizing the Profile and Risk Factors of Suicide: A Perspective from a Case–Control Study Focused on a Northern Region of Spain

M Sáenz-Aldea, MT Zarrabeitia… - International journal of …, 2022 - mdpi.com
Suicide is a major public health problem the prevention of which has become a priority, and,
to this end, knowledge of its risk factors is essential. This study aims to evaluate the impact of …

The development and implementation of a custom-tailored suicide response training for Muslim communities

R Awaad, M Midani, T Ali, MS Sifat… - Journal of religion and …, 2024 - Springer
Research indicates that the suicide attempt rate among American Muslims is at least twice
the rate of the national US average and follows a different trend of suicide behavior …