COVID-19 mechanisms in the human body—What we know so far
More than one and a half years have elapsed since the commencement of the coronavirus
disease 2019 (COVID-19) pandemic, and the world is struggling to contain it. Being caused …
disease 2019 (COVID-19) pandemic, and the world is struggling to contain it. Being caused …
Extracellular vesicle-based therapy for COVID-19: Promises, challenges and future prospects
The COVID-19 pandemic has become a serious concern and has negatively impacted
public health and the economy. It primarily targets the lungs, causing acute respiratory …
public health and the economy. It primarily targets the lungs, causing acute respiratory …
The NSP4 T492I mutation increases SARS-CoV-2 infectivity by altering non-structural protein cleavage
X Lin, Z Sha, J Trimpert, D Kunec, C Jiang, Y Xiong… - Cell Host & Microbe, 2023 - cell.com
The historically dominant SARS-CoV-2 Delta variant and the currently dominant Omicron
variants carry a T492I substitution within the non-structural protein 4 (NSP4). Based on in …
variants carry a T492I substitution within the non-structural protein 4 (NSP4). Based on in …
Angiotensin system polymorphisms' in SARS-CoV-2 positive patients: assessment between symptomatic and asymptomatic patients: a pilot study
C Cafiero, F Rosapepe, R Palmirotta, A Re… - Pharmacogenomics …, 2021 - Taylor & Francis
Introduction The renin–angiotensin–aldosterone system (RAAS), a metabolic cascade
regulating pressure and circulating blood volume, has been considered the main system …
regulating pressure and circulating blood volume, has been considered the main system …
COVID‐19‐induced autoimmune thyroiditis: Exploring molecular mechanisms
Severe acute respiratory syndrome coronavirus‐2 (SARS‐CoV‐2) damages multiple
organs, including the thyroid, by direct invasion and cell entry via angiotensin‐converting …
organs, including the thyroid, by direct invasion and cell entry via angiotensin‐converting …
Emerging SARS‐CoV‐2 variants can potentially break set epidemiological barriers in COVID‐19
Young age, female sex, absence of comorbidities, and prior infection or vaccination are
known epidemiological barriers for contracting the new infection and/or increased disease …
known epidemiological barriers for contracting the new infection and/or increased disease …
COVID-19 Biogenesis and Intracellular Transport
AA Mironov, MA Savin, GV Beznoussenko - International journal of …, 2023 - mdpi.com
SARS-CoV-2 is responsible for the COVID-19 pandemic. The structure of SARS-CoV-2 and
most of its proteins of have been deciphered. SARS-CoV-2 enters cells through the …
most of its proteins of have been deciphered. SARS-CoV-2 enters cells through the …
Molecular and computational analysis of spike protein of newly emerged omicron variant in comparison to the delta variant of SARS-CoV-2 in Iraq
PMA Rashid, GF Salih - Molecular biology reports, 2022 - Springer
Abstract Background The Severe Acute Respiratory Syndrome Coronavirus (SARS-CoV-2)
has had a major impact on world health over the last 2 years. The emergence of SARS-CoV …
has had a major impact on world health over the last 2 years. The emergence of SARS-CoV …
VF-Pred: Predicting virulence factor using sequence alignment percentage and ensemble learning models
S Singh, NQK Le, C Wang - Computers in Biology and Medicine, 2024 - Elsevier
This study introduces VF-Pred, a novel framework developed for the purpose of detecting
virulence factors (VFs) through the analysis of genomic data. VFs are crucial for pathogens …
virulence factors (VFs) through the analysis of genomic data. VFs are crucial for pathogens …
High circulating levels of the homeostatic chemokines CCL19 and CCL21 predict mortality and disease severity in COVID-19
A Tveita, SL Murphy, JC Holter, AB Kildal… - The Journal of …, 2022 - academic.oup.com
Background Immune dysregulation is a major factor in the development of severe
coronavirus disease 2019 (COVID-19). The homeostatic chemokines CCL19 and CCL21 …
coronavirus disease 2019 (COVID-19). The homeostatic chemokines CCL19 and CCL21 …