Lung under attack by COVID-19-induced cytokine storm: pathogenic mechanisms and therapeutic implications

C Pelaia, C Tinello, A Vatrella… - Therapeutic …, 2020 - journals.sagepub.com
The lung is a key target of the cytokine storm that can be triggered by severe acute
respiratory syndrome coronavirus-2 (SARS-CoV-2), responsible for the widespread clinical …

Corticosteroids for pneumonia

A Stern, K Skalsky, T Avni, E Carrara… - Cochrane Database …, 2017 - cochranelibrary.com
Background Pneumonia is a common and potentially serious illness. Corticosteroids have
been suggested for the treatment of different types of infection, however their role in the …

Analysis of factors associated with disease outcomes in hospitalized patients with 2019 novel coronavirus disease

W Liu, ZW Tao, L Wang, ML Yuan, K Liu… - Chinese medical …, 2020 - mednexus.org
Background Since early December 2019, the 2019 novel coronavirus disease (COVID-19)
has caused pneumonia epidemic in Wuhan, Hubei province of China. This study aimed to …

Severe COVID-19: a review of recent progress with a look toward the future

P Xie, W Ma, H Tang, D Liu - Frontiers in Public Health, 2020 - frontiersin.org
The novel coronavirus disease 2019 (COVID-19) is an acute infectious disease caused by
infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Currently …

Integrative physiology of pneumonia

LJ Quinton, AJ Walkey, JP Mizgerd - Physiological reviews, 2018 - journals.physiology.org
Pneumonia is a type of acute lower respiratory infection that is common and severe. The
outcome of lower respiratory infection is determined by the degrees to which immunity is …

Corticosteroids as adjunctive therapy in the treatment of influenza

L Lansbury, C Rodrigo, J Leonardi‐Bee… - Cochrane Database …, 2019 - cochranelibrary.com
Background Specific treatments for influenza are limited to neuraminidase inhibitors and
adamantanes. Corticosteroids show evidence of benefit in sepsis and related conditions …

[HTML][HTML] Diagnosis and treatment of acute pulmonary inflammation in critically ill patients: the role of inflammatory biomarkers

S Chalmers, A Khawaja, PM Wieruszewski… - World journal of …, 2019 - ncbi.nlm.nih.gov
Pneumonia and acute respiratory distress syndrome are common and important causes of
respiratory failure in the intensive care unit with a significant impact on morbidity, mortality …

Challenges in severe community-acquired pneumonia: a point-of-view review

A Torres, JD Chalmers, CS Dela Cruz… - Intensive care …, 2019 - Springer
Purpose Severe community-acquired pneumonia (SCAP) is still associated with substantial
morbidity and mortality. In this point-of-view review paper, a group of experts discuss the …

Corticosteroids in patients hospitalized with community-acquired pneumonia: systematic review and individual patient data metaanalysis

M Briel, SMC Spoorenberg, D Snijders… - Clinical Infectious …, 2018 - academic.oup.com
Background Our aim was to evaluate the benefits and harms of adjunctive corticosteroids in
adults hospitalized with community-acquired pneumonia (CAP) using individual patient data …

Community-acquired pneumonia in adults: diagnosis and management

A Kaysin, AJ Viera - American family physician, 2016 - aafp.org
Community-acquired pneumonia is a leading cause of death. Risk factors include older age
and medical comorbidities. Diagnosis is suggested by a history of cough, dyspnea, pleuritic …