Metformin has been used for over 40 years as an effective glucose-lowering agent in type 2
(noninsulin-dependent) diabetes mellitus. Typically it reduces basal and postprandial …

The content of In the Clinic is drawn from the clinical information and education resources of
the American College of Physicians (ACP), including PIER (Physicians' Information and …

Objective: To evaluate efficacy and safety of saxagliptin as add-on therapy in patients with
type 2 diabetes (T2D) with inadequate glycemic control on insulin alone or combined with …

Drug-induced weight gain is a serious side effect of many commonly used drugs leading to
noncompliance with therapy and to exacerbation of comorbid conditions related to obesity …

Diabetes mellitus (DM), or simply diabetes, is a group of metabolic diseases in which a
person has high blood sugar, either because the body does not produce enough insulin, or …

For decades, sulfonylureas (SUs) have been important drugs in the antidiabetic therapeutic
armamentarium. They have been used as monotherapy as well as combination therapy …

Several new pharmacological agents have recently been developed to optimise the
management of type 2 (non-insulin—dependent) diabetes mellitus. The aim of this article is …

Oral therapy for type 2 diabetes mellitus, when used appropriately, can safely assist patients
to achieve glycaemic targets in the short to medium term. However, the progressive nature of …

OBJECTIVE—To investigate the metabolic effects of metformin, as compared with placebo,
in type 2 diabetic patients intensively treated with insulin. RESEARCH DESIGN AND …

De NHG-Standaard Diabetes mellitus type 2 geeft richtlijnen voor de diagnostiek,
behandeling en begeleiding van volwassen patiënten met deze ziekte door de huisarts. 1 …