Intravenous fluid therapy in patients with severe acute pancreatitis admitted to the intensive care unit: a narrative review

A Crosignani, S Spina, F Marrazzo, S Cimbanassi… - Annals of Intensive …, 2022 - Springer
Patients with acute pancreatitis (AP) often require ICU admission, especially when signs of
multiorgan failure are present, a condition that defines AP as severe. This disease is …

Critical thresholds: key to unlocking the door to the prevention and specific treatments for acute pancreatitis

SG Barreto, A Habtezion, A Gukovskaya, A Lugea… - Gut, 2021 - gut.bmj.com
Acute pancreatitis (AP), an acute inflammatory disorder of the exocrine pancreas, is one of
the most common gastrointestinal diseases encountered in emergency departments with no …

Sitagliptin activates the p62–Keap1–Nrf2 signalling pathway to alleviate oxidative stress and excessive autophagy in severe acute pancreatitis-related acute lung …

L Kong, J Deng, X Zhou, B Cai, B Zhang, X Chen… - Cell death & …, 2021 - nature.com
Acute lung injury (ALI) is a complication of severe acute pancreatitis (SAP). Sitagliptin (SIT)
is a DPP4 inhibitor that exerts anti-inflammatory and antioxidant effects; however, its …

[PDF][PDF] 重症急性胰腺炎预防与阻断急诊专家共识

P HealthCare - 临床急诊杂志, 2022 - whuhzzs.com
急性胰腺炎是急诊科常见的严重消化系统疾病之一, 近年来急诊科收治的急性胰腺炎患者有增无
减. 急诊科早期积极有效地处理可以减轻胰腺炎带来的器官功能损害, 改善患者预后 …

Sex-related differences of acute and chronic pancreatitis in adults

M Drake, SJM Dodwad, J Davis, LS Kao, Y Cao… - Journal of clinical …, 2021 - mdpi.com
The incidence of acute and chronic pancreatitis is increasing in the United States. Rates of
acute pancreatitis (AP) are similar in both sexes, but chronic pancreatitis (CP) is more …

Experimental acute pancreatitis models: history, current status, and role in translational research

X Yang, L Yao, X Fu, R Mukherjee, Q Xia… - Frontiers in …, 2020 - frontiersin.org
Acute pancreatitis is a potentially severe inflammatory disease that may be associated with a
substantial morbidity and mortality. Currently there is no specific treatment for the disease …

[HTML][HTML] The role of pancreatic infiltrating innate immune cells in acute pancreatitis

C Peng, Z Li, X Yu - International journal of medical sciences, 2021 - ncbi.nlm.nih.gov
Acute pancreatitis (AP) is a leading cause of gastrointestinal-related hospital admissions
with significant morbidity and mortality. Although the underlying pathophysiology of AP is …

Assessment of prophylactic carbapenem antibiotics administration for severe acute pancreatitis: an updated systematic review and meta-analysis

D Guo, W Dai, J Shen, M Zhang, Y Shi, K Jiang, L Guo - Digestion, 2022 - karger.com
Background: The effectiveness of prophylactic antibiotics in severe acute pancreatitis (SAP)
remains a debatable issue. This meta-analysis aimed to determine the efficacy of …

Matrine alleviates oxidative stress and ferroptosis in severe acute pancreatitis-induced acute lung injury by activating the UCP2/SIRT3/PGC1α pathway

H Jin, K Zhao, J Li, Z Xu, S Liao, S Sun - International …, 2023 - Elsevier
Acute lung injury (ALI) is one of the most serious complications of severe acute pancreatitis
(SAP). Matrine is well known for its powerful antioxidant and antiapoptotic properties …

The systemic immune-inflammation index may be a novel and strong marker for the accurate early prediction of acute kidney injury in severe acute pancreatitis …

L Lu, Y Feng, Y Liu, H Tan, G Dai, S Liu… - Journal of InvestIgatIve …, 2022 - Taylor & Francis
Objective This research was performed to investigate the correlation between acute kidney
injury (AKI) and systemic immune-inflammation index (SII) in severe acute pancreatitis (SAP) …