Biological age in healthy elderly predicts aging-related diseases including dementia

JW Wu, A Yaqub, Y Ma, W Koudstaal, A Hofman… - Scientific reports, 2021 - nature.com
Application of biological age as a measure of an individual´ s health status offers new
perspectives into extension of both lifespan and healthspan. While algorithms predicting …

A proposed panel of biomarkers of healthy ageing

J Lara, R Cooper, J Nissan, AT Ginty, KT Khaw… - BMC medicine, 2015 - Springer
Background There is no criterion reference for assessing healthy ageing and this creates
difficulties when conducting and comparing research on ageing across studies. A cardinal …

T cell fitness and autologous CAR T cell therapy in haematologic malignancy

PH Mehta, S Fiorenza, RM Koldej… - Frontiers in …, 2021 - frontiersin.org
A range of emerging therapeutic approaches for the treatment of cancer aim to induce or
augment endogenous T cell responses. Chimeric antigen receptor (CAR) T cell therapy …

[图书][B] Beyond successful and active ageing: A theory of model ageing

V Timonen - 2016 - books.google.com
This controversial book argues that concepts such as 'successful'and 'active'ageing-
ubiquitous terms in research, marketing and policy making concerned with older adults–are …

Periodontitis and accelerated biological aging: A geroscience approach

G Baima, M Romandini, F Citterio… - Journal of Dental …, 2022 - journals.sagepub.com
As the whole world is epidemically aging, the burden of periodontitis and tooth loss is
becoming a major health concern. Growing meta-epidemiological data implicate chronic …

[HTML][HTML] Middle-age high normal serum sodium as a risk factor for accelerated biological aging, chronic diseases, and premature mortality

NI Dmitrieva, A Gagarin, D Liu, CO Wu, M Boehm - EBioMedicine, 2023 - thelancet.com
Background It is known that some people age faster than others, some people live into old
age disease-free, while others develop age-related chronic diseases. With a rapidly aging …

Maintaining healthy behavior: A prospective study of psychological well-being and physical activity

ES Kim, LD Kubzansky, J Soo… - Annals of Behavioral …, 2017 - academic.oup.com
Background Although higher psychological well-being has been linked with a range of
positive biological processes and health outcomes, the prospective association between …

Methylation-based biological age and breast cancer risk

JK Kresovich, Z Xu, KM O'Brien… - JNCI: Journal of the …, 2019 - academic.oup.com
Background Age is one of the strongest predictors of cancer, chronic disease, and mortality,
but biological responses to aging differ among people. Epigenetic DNA modifications have …

DNA methylation‐based biological aging and cancer risk and survival: Pooled analysis of seven prospective studies

PA Dugué, JK Bassett, JHE Joo… - … journal of cancer, 2018 - Wiley Online Library
The association between aging and cancer is complex. Recent studies have developed
measures of biological aging based on DNA methylation and called them “age …

Heterogeneity of human aging and its assessment

A Mitnitski, SE Howlett… - Journals of Gerontology …, 2017 - academic.oup.com
Understanding the heterogeneity in health of older adults is a compelling question in the
biology of aging. We analyzed the performance of five measures of health heterogeneity …