Exercise training prevents age‐related decline in muscle function. Targeting epigenetic aging is a promising actionable mechanism and late‐life exercise mitigates epigenetic aging …
To define metrics of phenotypic aging, it is essential to identify biological and environmental factors that influence the pace of aging. Previous attempts to develop aging metrics were …
The ability to control one's own emotions, thoughts, and behaviors in early life predicts a range of positive outcomes in later life, including longevity. Does it also predict how well …
Despite the sustained trend of decreasing overall cancer incidence, the number of elderly patients with cancer will considerably increase in the coming years, as the incidence of …
Stem cell dysfunction drives many age-related disorders. Identifying mechanisms that initially compromise stem cell behavior represent early targets to promote tissue function …
NI Dmitrieva, A Gagarin, D Liu, CO Wu, M Boehm - EBioMedicine, 2023 - thelancet.com
Background It is known that some people age faster than others, some people live into old age disease-free, while others develop age-related chronic diseases. With a rapidly aging …
EM Crimmins - Ageing research reviews, 2020 - Elsevier
This paper focuses on the social hallmarks of aging including low lifetime socioeconomic status, adversity in childhood and adulthood, being a member of a minority group, adverse …
Background: A number of large-scale population studies have provided valuable information about physical performance in aged individuals; however, there is little information about …
The human brain is plastic, ie it can show structural changes in response to the altered environment. Physical activity (PA) is a lifestyle factor which has significant associations with …