[HTML][HTML] Small molecule metabolites: discovery of biomarkers and therapeutic targets
S Qiu, Y Cai, H Yao, C Lin, Y Xie, S Tang… - Signal Transduction and …, 2023 - nature.com
Metabolic abnormalities lead to the dysfunction of metabolic pathways and metabolite
accumulation or deficiency which is well-recognized hallmarks of diseases. Metabolite …
accumulation or deficiency which is well-recognized hallmarks of diseases. Metabolite …
[PDF][PDF] Serotonin reduction in post-acute sequelae of viral infection
AC Wong, AS Devason, IC Umana, TO Cox… - Cell, 2023 - cell.com
Post-acute sequelae of COVID-19 (PASC," Long COVID") pose a significant global health
challenge. The pathophysiology is unknown, and no effective treatments have been found to …
challenge. The pathophysiology is unknown, and no effective treatments have been found to …
[HTML][HTML] Glutathione deficiency in the pathogenesis of SARS-CoV-2 infection and its effects upon the host immune response in severe COVID-19 disease
CA Labarrere, GS Kassab - Frontiers in Microbiology, 2022 - frontiersin.org
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) that causes coronavirus
disease 19 (COVID-19) has numerous risk factors leading to severe disease with high …
disease 19 (COVID-19) has numerous risk factors leading to severe disease with high …
[HTML][HTML] Signatures of mitochondrial dysfunction and impaired fatty acid metabolism in plasma of patients with post-acute sequelae of COVID-19 (PASC)
Exercise intolerance is a major manifestation of post-acute sequelae of severe acute
respiratory syndrome coronavirus infection (PASC, or “long-COVID”). Exercise intolerance in …
respiratory syndrome coronavirus infection (PASC, or “long-COVID”). Exercise intolerance in …
MetaboliteCOVID: A manually curated database of metabolite markers for COVID-19
L Ren, L Ning, Y Yang, T Yang, X Li, S Tan, P Ge… - Computers in Biology …, 2023 - Elsevier
In the realm of unraveling COVID-19's intricacies, numerous metabolomic investigations
have been conducted to discern the unique metabolic traits exhibited within infected …
have been conducted to discern the unique metabolic traits exhibited within infected …
[HTML][HTML] Metabolomics as a powerful tool for diagnostic, pronostic and drug intervention analysis in COVID-19
C Bruzzone, R Conde, N Embade, JM Mato… - Frontiers in molecular …, 2023 - frontiersin.org
COVID-19 currently represents one of the major health challenges worldwide. Albeit its
infectious character, with onset affectation mainly at the respiratory track, it is clear that the …
infectious character, with onset affectation mainly at the respiratory track, it is clear that the …
Sympathetic nervous activation, mitochondrial dysfunction and outcome in acutely decompensated cirrhosis: the metabolomic prognostic models (CLIF-C MET)
E Weiss, C de la Peña-Ramirez, F Aguilar, JJ Lozano… - Gut, 2023 - gut.bmj.com
Background and aims Current prognostic scores of patients with acutely decompensated
cirrhosis (AD), particularly those with acute-on-chronic liver failure (ACLF), underestimate …
cirrhosis (AD), particularly those with acute-on-chronic liver failure (ACLF), underestimate …
MBROLE3: improved functional enrichment of chemical compounds for metabolomics data analysis
J Lopez-Ibañez, F Pazos… - Nucleic Acids Research, 2023 - academic.oup.com
Abstract MBROLE (Metabolites Biological Role) facilitates the biological interpretation of
metabolomics experiments. It performs enrichment analysis of a set of chemical compounds …
metabolomics experiments. It performs enrichment analysis of a set of chemical compounds …
[HTML][HTML] Plasma metabolomics and gene regulatory networks analysis reveal the role of nonstructural SARS-CoV-2 viral proteins in metabolic dysregulation in COVID …
VA Ivanisenko, EV Gaisler, NV Basov, AD Rogachev… - Scientific Reports, 2022 - nature.com
Metabolomic analysis of blood plasma samples from COVID-19 patients is a promising
approach allowing for the evaluation of disease progression. We performed the …
approach allowing for the evaluation of disease progression. We performed the …
[HTML][HTML] Integrative plasma metabolic and lipidomic modelling of SARS-CoV-2 Infection in relation to clinical severity and early mortality prediction
An integrative multi-modal metabolic phenotyping model was developed to assess the
systemic plasma sequelae of SARS-CoV-2 (rRT-PCR positive) induced COVID-19 disease …
systemic plasma sequelae of SARS-CoV-2 (rRT-PCR positive) induced COVID-19 disease …