Diabetes, hypertension, body mass index, smoking and COVID-19-related mortality: a systematic review and meta-analysis of observational studies

Y Mahamat-Saleh, T Fiolet, ME Rebeaud, M Mulot… - BMJ open, 2021 - bmjopen.bmj.com
Objectives We conducted a systematic literature review and meta-analysis of observational
studies to investigate the association between diabetes, hypertension, body mass index …

Risks and impact of angiotensin-converting enzyme inhibitors or angiotensin-receptor blockers on SARS-CoV-2 infection in adults: a living systematic review

K Mackey, VJ King, S Gurley, M Kiefer… - Annals of internal …, 2020 - acpjournals.org
An update is available for this article. Background: The role of angiotensin-converting
enzyme inhibitors (ACEIs) and angiotensin-receptor blockers (ARBs) in coronavirus disease …

First and second waves of coronavirus disease-19: A comparative study in hospitalized patients in Reus, Spain

S Iftimie, AF López-Azcona, I Vallverdú… - PloS one, 2021 - journals.plos.org
Many countries have seen a two-wave pattern in reported cases of coronavirus disease-19
during the 2020 pandemic, with a first wave during spring followed by the current second …

Antihypertensive drugs and COVID-19 risk: a cohort study of 2 million hypertensive patients

L Semenzato, J Botton, J Drouin, B Baricault… - …, 2021 - Am Heart Assoc
After initially hypothesizing a positive relationship between use of renin-angiotensin-
aldosterone system inhibitors and risk of coronavirus disease 2019 (COVID-19), more recent …

Efficacy of losartan in hospitalized patients with COVID-19–induced lung injury: a randomized clinical trial

MA Puskarich, NE Ingraham, LH Merck… - JAMA network …, 2022 - jamanetwork.com
Importance SARS-CoV-2 viral entry may disrupt angiotensin II (AII) homeostasis,
contributing to COVID-19 induced lung injury. AII type 1 receptor blockade mitigates lung …

A comprehensive guide to the pharmacologic regulation of angiotensin converting enzyme 2 (ACE2), the SARS-CoV-2 entry receptor

M Oz, DE Lorke, N Kabbani - Pharmacology & therapeutics, 2021 - Elsevier
The recent emergence of coronavirus disease-2019 (COVID-19) as a global pandemic has
prompted scientists to address an urgent need for defining mechanisms of disease …

Late phase of COVID‐19 pandemic in General Cardiology. A position paper of the ESC Council for Cardiology Practice

D Richter, L Guasti, F Koehler, A Squizzato… - ESC Heart …, 2021 - Wiley Online Library
Cardiovascular (CV) engagement in coronavirus disease 2019 (COVID‐19) is a huge
determinant of prognosis during the acute phase of the disease. However, little is known …

Renin‐angiotensin aldosterone system inhibitors and COVID‐19: a systematic review and meta‐analysis revealing critical bias across a body of observational …

J Loader, FC Taylor, E Lampa… - Journal of the American …, 2022 - Am Heart Assoc
Background Renin‐angiotensin aldosterone system (RAAS) inhibitor—COVID‐19 studies,
observational in design, appear to use biased methods that can distort the interaction …

Lopinavir/ritonavir and darunavir/cobicistat in hospitalized COVID-19 patients: findings from the multicenter Italian CORIST study

A Di Castelnuovo, S Costanzo, A Antinori… - Frontiers in …, 2021 - frontiersin.org
Background: Protease inhibitors have been considered as possible therapeutic agents for
COVID-19 patients. Objectives: To describe the association between lopinavir/ritonavir …

An umbrella review and meta‐analysis of renin–angiotensin system drugs use and COVID‐19 outcomes

A Kurdi, T Mueller, N Weir - European journal of clinical …, 2023 - Wiley Online Library
Background Despite the availability of extensive literature on the effect of angiotensin‐
converting enzyme inhibitors (ACEIs)/angiotensin‐receptor blockers (ARBs) on COVID‐19 …