Modified parental histones are segregated symmetrically to daughter DNA strands during
replication and can be inherited through mitosis. How this may sustain the epigenome and …

Chromatin landscapes are disrupted during DNA replication and must be restored faithfully
to maintain genome regulation and cell identity. The histone H3-H4 modification landscape …

Decades of work on the spatiotemporal organization of mammalian DNA replication timing
(RT) continues to unveil novel correlations with aspects of transcription and chromatin …

During cell renewal, epigenetic information needs to be precisely restored to maintain cell
identity and genome integrity following DNA replication. The histone mark H3K27me3 is …

DNA replication produces a global disorganization of chromatin structure that takes hours to
be restored. However, how these chromatin rearrangements affect the regulation of gene …

Introduction: Epigenetics studies gene expression changes influenced by environmental
and lifestyle factors, linked to health conditions like reproductive aging. Male reproductive …

During every cell cycle, both the genome and the associated chromatin must be accurately
replicated. Chromatin Assembly Factor-1 (CAF-1) is a key regulator of chromatin replication …

The inheritance of parental histones across the replication fork is thought to mediate
epigenetic memory. Here, we reveal that fission yeast Mrc1 (CLASPIN in humans) binds H3 …

Two recent studies in Molecular Cell 1 and Nature 2 show that evicted RNA polymerases
reassociate rapidly with post-replicative chromatin and proceed into an unusual transcription …

Before each cell division, eukaryotic cells must replicate their chromosomes to ensure the
accurate transmission of genetic information. Chromosome replication involves more than …