Microbiome and human health: current understanding, engineering, and enabling technologies

N Aggarwal, S Kitano, GRY Puah, S Kittelmann… - Chemical …, 2022 - ACS Publications
The human microbiome is composed of a collection of dynamic microbial communities that
inhabit various anatomical locations in the body. Accordingly, the coevolution of the …

The gut microbiota in anxiety and depression–A systematic review

CA Simpson, C Diaz-Arteche, D Eliby… - Clinical psychology …, 2021 - Elsevier
Growing evidence indicates the community of microorganisms throughout the
gastrointestinal tract,(ie, gut microbiota), is associated with anxiety and depressive …

Multi-omics analyses of serum metabolome, gut microbiome and brain function reveal dysregulated microbiota-gut-brain axis in bipolar depression

Z Li, J Lai, P Zhang, J Ding, J Jiang, C Liu… - Molecular …, 2022 - nature.com
The intricate processes of microbiota-gut-brain communication in modulating human
cognition and emotion, especially in the context of mood disorders, have remained elusive …

Implications of gut microbiota in neurodegenerative diseases

H Zhang, Y Chen, Z Wang, G Xie, M Liu… - Frontiers in …, 2022 - frontiersin.org
The morbidity associated with neurodegenerative diseases (NDs) is increasing, posing a
threat to the mental and physical quality of life of humans. The crucial effect of microbiota on …

The gut microbiota and depressive symptoms across ethnic groups

JA Bosch, M Nieuwdorp, AH Zwinderman… - Nature …, 2022 - nature.com
The gut microbiome is thought to play a role in depressive disorders, which makes it an
attractive target for interventions. Both the microbiome and depressive symptom levels vary …

Reductions in anti-inflammatory gut bacteria are associated with depression in a sample of young adults

RT Liu, AD Rowan-Nash, AE Sheehan… - Brain, behavior, and …, 2020 - Elsevier
We assessed the gut microbiota of 90 American young adults, comparing 43 participants
with major depressive disorder (MDD) and 47 healthy controls, and found that the MDD …

The gut microbiota–brain axis in neurological disorder

H Ullah, S Arbab, Y Tian, C Liu, Y Chen… - Frontiers in …, 2023 - frontiersin.org
The gut microbiota (GM) plays an important role in the physiology and pathology of the host.
Microbiota communicate with different organs of the organism by synthesizing hormones …

Ingestion of Lactobacillus intestinalis and Lactobacillus reuteri causes depression- and anhedonia-like phenotypes in antibiotic-treated mice via the vagus nerve

S Wang, T Ishima, J Zhang, Y Qu, L Chang… - Journal of …, 2020 - Springer
Background The brain–gut–microbiota axis plays a role in the pathogenesis of stress-related
disorders such as depression. In this study, we examined the effects of fecal microbiota …

Bacterial metabolites of human gut microbiota correlating with depression

OV Averina, YA Zorkina, RA Yunes, AS Kovtun… - International journal of …, 2020 - mdpi.com
Depression is a global threat to mental health that affects around 264 million people
worldwide. Despite the considerable evolution in our understanding of the pathophysiology …

Gut microbiota metabolites in major depressive disorder—Deep insights into their pathophysiological role and potential translational applications

MA Ortega, MA Alvarez-Mon, C García-Montero… - Metabolites, 2022 - mdpi.com
The gut microbiota is a complex and dynamic ecosystem essential for the proper functioning
of the organism, affecting the health and disease status of the individuals. There is …