Heterogeneity of ILC2s in the intestine; homeostasis and pathology

S Sunaga, J Tsunoda, T Teratani, Y Mikami… - Frontiers in …, 2022 - frontiersin.org
Group 2 innate lymphoid cells (ILC2s) were identified in 2010 as a novel lymphocyte subset
lacking antigen receptors, such as T-cell or B-cell receptors. ILC2s induce local immune …

Overview of single‐cell RNA sequencing analysis and its application to spermatogenesis research

T Suzuki - Reproductive Medicine and Biology, 2023 - Wiley Online Library
Background Single‐cell transcriptomics allows parallel analysis of multiple cell types in
tissues. Because testes comprise somatic cells and germ cells at various stages of …

Crossing the valley of death: toward translational research regarding ILC2

T Yashiro, K Moro - Allergology International, 2023 - jstage.jst.go.jp
abstract Group 2 innate lymphoid cells (ILC2s) are tissue-resident innate lymphoid cells that
express the transcription factor GATA3 as a master regulator, which leads to the production …

The epidermis: Redox governor of health and diseases

Y Ishitsuka, DR Roop - Antioxidants, 2021 - mdpi.com
A functional epithelial barrier necessitates protection against dehydration, and ichthyoses
are caused by defects in maintaining the permeability barrier in the stratum corneum (SC) …

The Roles of Various Immune Cell Populations in Immune Response against Helminths

J Lekki-Jóźwiak, P Bąska - International Journal of Molecular Sciences, 2023 - mdpi.com
Helminths are multicellular parasites that are a substantial problem for both human and
veterinary medicine. According to estimates, 1.5 billion people suffer from their infection …

[HTML][HTML] Bone Marrow Progenitors and IL-2 Signaling Contribute to the Strain Differences of Kidney Innate Lymphoid Cells

S Ryu, HY Kim - Immune Network, 2023 - ncbi.nlm.nih.gov
Innate lymphoid cells (ILCs) are critical immune-response mediators. Although they largely
reside in mucosal tissues, the kidney also bears substantial numbers. Nevertheless, kidney …

Allergic and non-allergic asthma: Translational research in immunology

E Boberg - 2022 - gupea.ub.gu.se
Asthma is a chronic heterogeneous respiratory disease affecting more than 300 million
people globally. The different phenotypes, including allergic and nonallergic asthma, are …

[PDF][PDF] C5aR1 functions in cellular networking of ILC2 in health and

RÜ KORKMAZ - 2022 - zhb.uni-luebeck.de
Worldwide more than 300 million people are affected by asthma, a heterogeneous disease
characterized by chronic airway inflammation. Allergic asthma is the most common asthma …