Roles of oxytocin in stress responses, allostasis and resilience

Y Takayanagi, T Onaka - International journal of molecular sciences, 2021 - mdpi.com
Oxytocin has been revealed to work for anxiety suppression and anti-stress as well as for
psychosocial behavior and reproductive functions. Oxytocin neurons are activated by …

Neural functions of hypothalamic oxytocin and its regulation

P Wang, SC Wang, X Liu, S Jia, X Wang, T Li… - ASN …, 2022 - journals.sagepub.com
Oxytocin (OT), a nonapeptide, has a variety of functions. Despite extensive studies on OT
over past decades, our understanding of its neural functions and their regulation remains …

The role of the central amygdala in alcohol dependence

M Roberto, D Kirson, S Khom - Cold Spring …, 2021 - perspectivesinmedicine.cshlp.org
Alcohol dependence is a chronically relapsing disorder characterized by compulsive drug-
seeking and drug-taking, loss of control in limiting intake, and the emergence of a …

Role of oxytocin in the control of stress and food intake

T Onaka, Y Takayanagi - Journal of neuroendocrinology, 2019 - Wiley Online Library
Oxytocin neurones in the hypothalamus are activated by stressful stimuli and food intake.
The oxytocin receptor is located in various brain regions, including the sensory information …

Oxytocin and vasopressin in the rodent hippocampus

NI Cilz, A Cymerblit‐Sabba… - Genes, Brain and …, 2019 - Wiley Online Library
The role of the hippocampus in social memory and behavior is under intense investigation.
Oxytocin (Oxt) and vasopressin (Avp) are two neuropeptides with many central actions …

Oxytocin blocks enhanced motivation for alcohol in alcohol dependence and blocks alcohol effects on GABAergic transmission in the central amygdala

BJ Tunstall, D Kirson, LJ Zallar, SA McConnell… - PLoS …, 2019 - journals.plos.org
Oxytocin administration has been reported to decrease consumption, withdrawal, and drug-
seeking associated with several drugs of abuse and thus represents a promising …

The role of oxytocin in alcohol and drug abuse

CE King, A Gano, HC Becker - Brain research, 2020 - Elsevier
The neuropeptide oxytocin (OXT) plays a key role in adaptive processes associated with
reward, tolerance, memory and stress responses. Through interactions with brain reward …

Oxytocin and rodent models of addiction

KC Leong, S Cox, C King, H Becker… - International review of …, 2018 - Elsevier
Interest for the use of oxytocin as a treatment for addiction began over 40 years ago. Better
known for its roles in parturition, lactation and pair bonding, oxytocin also has anxiolytic …

The vagus nerve mediates the suppressing effects of peripherally administered oxytocin on methamphetamine self-administration and seeking in rats

NA Everett, AJ Turner, PA Costa, SJ Baracz… - …, 2021 - nature.com
The neuropeptide oxytocin has emerged as a promising pharmacotherapy for
methamphetamine (METH) addiction, and clinical trials of intranasal oxytocin are underway …

Oxytocin and vasopressin inhibit hyper-aggressive behaviour in socially isolated mice

O Tan, H Musullulu, JS Raymond, B Wilson… - …, 2019 - Elsevier
Despite the high prevalence of aggression across a wide range of disorders, there is a
severe lack of pharmacological treatments. Recent rodent studies have shown both centrally …