Modeling climate change impacts on vector-borne disease using machine learning models: Case study of Visceral leishmaniasis (Kala-azar) from Indian state of Bihar

S Kumar, A Srivastava, R Maity - Expert Systems with Applications, 2024 - Elsevier
Visceral leishmaniasis or Kala-azar (KA) is a Vector-Borne Disease (VBD) that remains the
second-largest parasitic killer across the globe (mortality rate: 75–95%). More than 60% of …

Diagnostic Tools for Cutaneous Leishmaniasis Caused by Leishmania donovani: A Narrative Review

SB Piyasiri, R Dewasurendra, N Samaranayake… - Diagnostics, 2023 - mdpi.com
Leishmaniasis, a neglected tropical disease, encompasses a spectrum of clinical conditions
and poses a significant risk of infection to over one billion people worldwide. Visceral …

Overview of Research on Leishmaniasis in Africa: Current Status, Diagnosis, Therapeutics, and Recent Advances Using By-Products of the Sargassaceae Family

FM Abdoul-Latif, K Oumaskour, N Abdallah, A Ainane… - Pharmaceuticals, 2024 - mdpi.com
Leishmaniasis in Africa, which has been designated as a priority neglected tropical disease
by various global organizations, exerts its impact on millions of individuals, primarily …

In vitro effect of alpha-bisabolol and its synthetic derivatives on macrophages, promastigotes, and amastigotes of Leishmania amazonensis and Leishmania infantum

LR Perin, LA Parreira, ECS Barcelos… - Natural Product …, 2023 - Taylor & Francis
Cutaneous and visceral leishmaniasis are public health problems in Africa, Asia, Europe,
and America. The treatment has a high cost and toxicity. Thus, this work aims to evaluate the …

Antileishmanial Effect of 1, 5-and 1, 8-Substituted Fused Naphthyridines

E Melcón-Fernandez, E Martín-Encinas, F Palacios… - Molecules, 2023 - mdpi.com
In the absence of a vaccine, there is a need to find new drugs for the treatment of neglected
tropical diseases, such as leishmaniasis, that can overcome the many drawbacks of those …

Review of Leishmaniasis Treatment: Can We See the Forest through the Trees?

M Shmueli, S Ben-Shimol - Pharmacy, 2024 - mdpi.com
There are three known clinical syndromes of leishmaniasis: cutaneous (CL),
mucocutaneous (MCL), and visceral disease (VL). In MCL and VL, treatment must be …

Understanding hypergammaglobulinemia in experimental or natural visceral leishmaniasis

CA de Carvalho, RM Hiramoto, LR Meireles… - Parasite …, 2024 - Wiley Online Library
Nonspecific hypergammaglobulinemia (HGG) occurs in symptomatic human visceral
leishmaniasis (VL) caused by LL infantum. This study assessed this finding in experimental …

Many faces of cutaneous leishmaniasis

İ An, NY Doni - Postgraduate Medical Journal, 2024 - academic.oup.com
Background Our objective in this study is to determine the atypical clinical presentations of
cutaneous leishmaniasis (CL) patients diagnosed in Şanlıurfa province. Methods This …

Leishmanial activity of Brazilian brown propolis and its diterpenes

LC Oliveira, V Pena Ribeiro, MFC Santos… - Natural Product …, 2023 - Taylor & Francis
Propolis is a natural product widely used in folk medicine. Among its various applications, its
antiparasitic properties stand out. Due to its great biodiversity, Brazil is a major producer of …

Delayed diagnosis among patients with visceral leishmaniasis

A Poloni, A Giacomelli, M Corbellino, R Grande… - Internal and Emergency …, 2023 - Springer
We aimed to estimate the diagnostic latency of patients with visceral leishmaniasis (VL). A
monocentric retrospective observational study was conducted including all confirmed cases …