SARS-CoV-2 infection and lung regeneration

F Zhao, Q Ma, Q Yue, H Chen - Clinical Microbiology Reviews, 2022 - Am Soc Microbiol
The lung is the primary site of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-
2)-induced immunopathology whereby the virus enters the host cells by binding to …

Emerging delivery approaches for targeted pulmonary fibrosis treatment

R Diwan, HN Bhatt, E Beaven, M Nurunnabi - Advanced drug delivery …, 2023 - Elsevier
Pulmonary fibrosis (PF) is a progressive, and life-threatening interstitial lung disease which
causes scarring in the lung parenchyma and thereby affects architecture and functioning of …

Stem cell-based therapy for pulmonary fibrosis

W Cheng, Y Zeng, D Wang - Stem Cell Research & Therapy, 2022 - Springer
Pulmonary fibrosis (PF) is a chronic and relentlessly progressive interstitial lung disease in
which the accumulation of fibroblasts and extracellular matrix (ECM) induces the destruction …

Role of PD-L1 in licensing immunoregulatory function of dental pulp mesenchymal stem cells

R Di Tinco, G Bertani, A Pisciotta, L Bertoni… - Stem Cell Research & …, 2021 - Springer
Background Dental pulp stem cells (DPSCs) are low immunogenic and hold
immunomodulatory properties that, along with their well-established multi-potency, might …

Role of MSC‐derived small extracellular vesicles in tissue repair and regeneration

BA Aguiar Koga, LA Fernandes, P Fratini… - Frontiers in Cell and …, 2023 - frontiersin.org
Mesenchymal stem cells (MSCs) are crucial for tissue homeostasis and repair, secreting
vesicles to the extracellular environment. Isolated exosomes were shown to affect …

Microfluidic tools for enhanced characterization of therapeutic stem cells and prediction of their potential antimicrobial secretome

P Marrazzo, V Pizzuti, S Zia, A Sargenti, D Gazzola… - Antibiotics, 2021 - mdpi.com
Antibiotic resistance is creating enormous attention on the development of new antibiotic-
free therapy strategies for bacterial diseases. Mesenchymal stromal stem cells (MSCs) are …

Efficacy and safety of human umbilical cord-derived mesenchymal stem cells for COVID-19 pneumonia: a meta-analysis of randomized controlled trials

Q Liu, F Ma, Y Zhong, G Wang, L Hu, Y Zhang… - Stem Cell Research & …, 2023 - Springer
Background Elevated levels of inflammatory factors are associated with poor prognosis in
coronavirus disease-19 (COVID-19). However, mesenchymal stem cells (MSCs) have …

Neutrophils and the systemic inflammatory response syndrome (SIRS)

JP Sikora, J Karawani, J Sobczak - International Journal of Molecular …, 2023 - mdpi.com
We are not entirely able to understand, assess, and modulate the functioning of the immune
system in clinical situations that lead to a systemic inflammatory response. In the search for …

Advances in nano-based drug delivery systems for the management of cytokine influx-mediated inflammation in lung diseases

N Gulati, DK Chellappan, R MacLoughlin… - Naunyn-Schmiedeberg's …, 2024 - Springer
Asthma, lung cancer, cystic fibrosis, tuberculosis, acute respiratory distress syndrome,
chronic obstructive pulmonary disease, and COVID-19 are few examples of inflammatory …

Mesenchymal stem cells and their small extracellular vesicles as crucial immunological efficacy for hepatic diseases

Y Tang, P Wu, L Li, W Xu, J Jiang - Frontiers in immunology, 2022 - frontiersin.org
Mesenchymal stem cell small extracellular vesicles (MSC-sEVs) are a priority for
researchers because of their role in tissue regeneration. sEVs act as paracrine factors and …