[HTML][HTML] Insights into SARS-CoV-2 genome, structure, evolution, pathogenesis and therapies: Structural genomics approach

AAT Naqvi, K Fatima, T Mohammad, U Fatima… - … et Biophysica Acta (BBA …, 2020 - Elsevier
The sudden emergence of severe respiratory disease, caused by a novel severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2), has recently become a public health …

A review of the toxicology presence and removal of ketoprofen through adsorption technology

J Georgin, DSP Franco, K da Boit Martinello… - Journal of …, 2022 - Elsevier
The present review was carried out to analyze the works developed using the adsorption
technology to remove the anti-inflammatory ketoprofen (KET). The main factors that inflated …

Covid-19 kills more men than women: an overview of possible reasons

A Capuano, F Rossi, G Paolisso - Frontiers in cardiovascular …, 2020 - frontiersin.org
The high mortality observed in Covid-19 patients may be related to unrecognized pulmonary
embolism, pulmonary thrombosis, or other underlying cardiovascular diseases. Recent data …

The management of surgical patients in the emergency setting during COVID-19 pandemic: the WSES position paper

B De Simone, E Chouillard, M Sartelli, WL Biffl… - World Journal of …, 2021 - Springer
Background Since the COVID-19 pandemic has occurred, nations showed their
unpreparedness to deal with a mass casualty incident of this proportion and severity, which …

Paracetamol-induced glutathione consumption: is there a link with severe COVID-19 illness?

P Sestili, C Fimognari - Frontiers in Pharmacology, 2020 - frontiersin.org
COVID-19 pandemic is posing an unprecedented sanitary threat: antiviral and host-directed
medications to treat the disease are urgently needed. A great effort has been paid to find …

Prior routine use of non-steroidal anti-inflammatory drugs (NSAIDs) and important outcomes in hospitalised patients with COVID-19

E Bruce, F Barlow-Pay, R Short… - Journal of Clinical …, 2020 - mdpi.com
Coronavirus disease 2019 (COVID-19) infection causes acute lung injury, resulting from
aggressive inflammation initiated by viral replication. There has been much speculation …

Therapeutic strategies to fight COVID‐19: Which is the status artis?

C Scavone, A Mascolo, C Rafaniello… - British Journal of …, 2022 - Wiley Online Library
COVID‐19 is a complex disease, and many difficulties are faced today especially in the
proper choice of pharmacological treatments. The role of antiviral agents for COVID‐19 is …

COVID‐19 breakthroughs: separating fact from fiction

P Dhillon, M Breuer, N Hirst - The FEBS journal, 2020 - Wiley Online Library
The newly recognised coronavirus SARS‐CoV‐2, causative agent of coronavirus disease
(COVID‐19), has caused a pandemic with huge ramifications for human interactions around …

Network pharmacology approach to decipher signaling pathways associated with target proteins of NSAIDs against COVID-19

KK Oh, M Adnan, DH Cho - Scientific reports, 2021 - nature.com
Non-steroidal anti-inflammatory drugs (NSAIDs) showed promising clinical efficacy toward
COVID-19 (Coronavirus disease 2019) patients as potent painkillers and anti-inflammatory …

Activation of the cholinergic anti-inflammatory pathway as a novel therapeutic strategy for COVID-19

Z Qin, K Xiang, DF Su, Y Sun, X Liu - Frontiers in Immunology, 2021 - frontiersin.org
The outbreak of coronavirus disease 2019 (COVID-19) underlined the urgent need for
alleviating cytokine storm. We propose here that activating the cholinergic anti-inflammatory …