Long‐COVID syndrome‐associated brain fog and chemofog: Luteolin to the rescue

TC Theoharides, C Cholevas, K Polyzoidis… - Biofactors, 2021 - Wiley Online Library
COVID‐19 leads to severe respiratory problems, but also to long‐COVID syndrome
associated primarily with cognitive dysfunction and fatigue. Long‐COVID syndrome …

Interleukin-1 and the NLRP3 inflammasome in COVID-19: Pathogenetic and therapeutic implications

N Potere, MG Del Buono, R Caricchio, PC Cremer… - …, 2022 - thelancet.com
A hyperinflammatory response during severe acute respiratory syndrome coronavirus 2
(SARS-CoV-2) infection crucially worsens clinical evolution of coronavirus disease 2019 …

Interleukin-6 is a biomarker for the development of fatal severe acute respiratory syndrome coronavirus 2 pneumonia

A Santa Cruz, A Mendes-Frias, AI Oliveira… - Frontiers in …, 2021 - frontiersin.org
Hyper-inflammatory responses induced by severe acute respiratory syndrome coronavirus 2
(SARS-CoV-2) are a major cause of disease severity and death. Predictive prognosis …

The SARS-CoV-2 protein ORF3a inhibits fusion of autophagosomes with lysosomes

Y Zhang, H Sun, R Pei, B Mao, Z Zhao, H Li, Y Lin, K Lu - Cell discovery, 2021 - nature.com
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has caused the ongoing
coronavirus disease 2019 pandemic. How SARS-CoV-2 regulates cellular responses to …

Vitamin D deficiency is associated with COVID‐19 positivity and severity of the disease

M Demir, F Demir, H Aygun - Journal of medical virology, 2021 - Wiley Online Library
The present study examined the relationship between polymerase chain reaction (PCR) test
positivity and clinical outcomes of vitamin D levels measured within the 6 months before the …

Inflammasome formation in the lungs of patients with fatal COVID-19

S Toldo, R Bussani, V Nuzzi, A Bonaventura… - Inflammation …, 2021 - Springer
Objective The orf8b protein of the coronavirus SARS-CoV, analogous to SARS-CoV-2,
triggers the NLRP3 inflammasome in macrophages in vitro. Deregulated inflammasome …

Calming the storm: natural immunosuppressants as adjuvants to target the cytokine storm in COVID-19

AE Peter, BV Sandeep, BG Rao… - Frontiers in …, 2021 - frontiersin.org
The COVID-19 pandemic has caused a global health crisis, with no specific antiviral to treat
the infection and the absence of a suitable vaccine to prevent it. While some individuals …

Increased interleukin-6 and macrophage chemoattractant protein-1 are associated with respiratory failure in COVID-19

M Jøntvedt Jørgensen, JC Holter, EE Christensen… - Scientific reports, 2020 - nature.com
In SARS-CoV-2 infection there is an urgent need to identify patients that will progress to
severe COVID-19 and may benefit from targeted treatment. In this study we analyzed plasma …

Physiological basis for using vitamin D to improve health

SJ Wimalawansa - Biomedicines, 2023 - mdpi.com
Vitamin D is essential for life—its sufficiency improves metabolism, hormonal release,
immune functions, and maintaining health. Vitamin D deficiency increases the vulnerability …

[HTML][HTML] Renal injury by SARS-CoV-2 infection: a systematic review

M Wang, H Xiong, H Chen, Q Li, XZ Ruan - Kidney Diseases, 2021 - karger.com
Background: SARS-CoV-2 infection can cause renal involvement, and severe renal
dysfunction is more common among patients with chronic comorbid conditions, especially …