Tumor-associated exosomes promote lung cancer metastasis through multiple mechanisms

C Jiang, N Zhang, X Hu, H Wang - Molecular Cancer, 2021 - Springer
As an important medium of intercellular communication, exosomes play an important role in
information transmission between tumor cells and their microenvironment. Tumor metastasis …

A study of miRNAs as cornerstone in lung cancer pathogenesis and therapeutic resistance: A focus on signaling pathways interplay

AS Doghish, A Ismail, MA Elrebehy… - … -Research and Practice, 2022 - Elsevier
Lung cancer (LC) is the most common cancer-related death globally, and many efforts have
been made to improve the patient care of LC patients, as well as the development of efficient …

The role of Exosomal miRNAs in cancer

C Li, T Zhou, J Chen, R Li, H Chen, S Luo… - Journal of translational …, 2022 - Springer
Exosomal miRNAs have attracted much attention due to their critical role in regulating genes
and the altered expression of miRNAs in virtually all cancers affecting humans (Sun et al. in …

Exosomes: another intercellular lipometabolic communication mediators in digestive system neoplasms?

S Li, R Dong, Z Kang, H Li, X Wu, T Li - Cytokine & growth factor reviews, 2023 - Elsevier
Neoplasms are one of the most concerned public health problems worldwide. Digestive
system neoplasms, with a high morbidity and mortality, is one of the most common malignant …

Exosomal proteins and lipids as potential biomarkers for lung cancer diagnosis, prognosis, and treatment

MT Hsu, YK Wang, YJ Tseng - Cancers, 2022 - mdpi.com
Simple Summary Exosomes (or extracellular vesicles) are known to mediate intercellular
communication and to transmit molecular signals between cells. Molecules carried by …

Structural characterisation and antitumor activity against non-small cell lung cancer of polysaccharides from Sanghuangporus vaninii

X Wan, X Jin, X Wu, X Yang, D Lin, C Li, Y Fu… - Carbohydrate …, 2022 - Elsevier
The medicinal fungus Sanghuangporus vaninii can be cultivated in large scale and has
outstanding antitumour activity. In this study, water-soluble S. vaninii polysaccharides …

Extracellular vesicle–based drug delivery in cancer immunotherapy

S Najafi, J Majidpoor, K Mortezaee - Drug Delivery and Translational …, 2023 - Springer
Extracellular vesicles (EVs) are a group of nanoscale membrane-bound organelles
including exosomes, microvesicles (MVs), membrane particles, and apoptotic bodies, which …

The role of exosomes in lung cancer metastasis and clinical applications: an updated review

L Yin, X Liu, X Shao, T Feng, J Xu, Q Wang… - Journal of Translational …, 2021 - Springer
Lung cancer is the leading cause of cancer-associated deaths accounting for 24% of all
cancer deaths. As a crucial phase of tumor progression, lung cancer metastasis is linked to …

Exosomal miR-338-3p suppresses non-small-cell lung cancer cells metastasis by inhibiting CHL1 through the MAPK signaling pathway

W Tian, X Yang, H Yang, M Lv, X Sun, B Zhou - Cell Death & Disease, 2021 - nature.com
Globally, lung cancer remains one of the most prevalent malignant cancers. However,
molecular mechanisms and functions involved in its pathogenesis have not been clearly …

Lipid nanocarrier-based drug delivery systems: therapeutic advances in the treatment of lung cancer

SJ Kim, N Puranik, D Yadav, JO Jin… - International Journal of …, 2023 - Taylor & Francis
Although various treatments are currently being developed, lung cancer still has a very high
mortality rate. Moreover, while various strategies for the diagnosis and treatment of lung …