Hepatocellular carcinoma: predisposing conditions and precursor lesions

MA Bailey, EM Brunt - Gastroenterology Clinics, 2002 - gastro.theclinics.com
Hepatocellular carcinoma (HCC) is the most common primary liver tumor [1–4] and the
fourth most common cancer in the world [5]. The prevalence varies with geographic location …

Karyometric analysis of liver cell dysplasia and hepatocellular carcinoma. Evidence against precancerous nature of liver cell dysplasia

A Henmi, T Uchida, T Shikata - Cancer, 1985 - Wiley Online Library
Karyometric analysis was performed with respect to anisonucleosis, nuclear deformity and
DNA content in cases of liver cell dysplasia (LCD) and hepatocellular carcinoma (HCC) …

[HTML][HTML] 乙型肝炎病毒慢性感染和肝癌发生

苏勤 - 世界华人消化杂志, 2003 - wjgnet.com
肝细胞癌(hepatocellular carcinoma, HCC) 是人类最常见的恶性肿瘤之一.
在世界范围内居男性最常见恶性肿瘤的第7 位, 居女性第9 位; 在中国被列为男性恶性肿瘤的第3 …

Current pathogenetic and molecular concepts in viral liver carcinogenesis

P Schirmacher, CE Rogler, HP Dienes - Virchows Archiv B, 1993 - Springer
Hepatocellular carcinoma (HCC) is one of the most frequent malignancies in humans and in
most cases a consequence of chronic infection of the liver by hepatotropic viruses (Hepatitis …

Immunohistochemical detection of bcl‐2 protein in liver lesions: bcl‐2 protein is expressed in hepatocellular carcinomas but not in liver cell dysplasia

M Zhao, NX Zhang, M Economou, I Blaha… - …, 1994 - Wiley Online Library
A proto‐oncogene, bcl‐2, encodes a protein that inhibits programmed cell death (apoptosis)
and may play a role in cell and tissue differentiation. As bcl‐2 appears to be involved in the …

Hepatocellular carcinoma: New and emerging risks

M Sherman - Digestive and Liver Disease, 2010 - Elsevier
The underlying liver diseases that put patients at risk for the development of hepatocellular
carcinoma (HCC) are well known. However, it is equally well known that not all patients with …

Large-cell change of hepatocytes in cirrhosis may represent a reaction to prolonged cholestasis

S Natarajan, ND Theise, SN Thung… - The American journal …, 1997 - journals.lww.com
Large-cell change of hepatocytes (LCC), also called liver cell dysplasia of large-cell type, is
a set of cytologic changes comprising nuclear and cytoplasmic enlargement, nuclear …

Ultrasonography-detected macroregenerative nodules in cirrhosis: a prospective study.

M Borzio, F Borzio, A Croce, M Sala, A Salmi… - …, 1997 - europepmc.org
Methods Macroregenerative nodule classification was based on recently proposed
histological criteria. Extranodular liver cell dysplasia was also evaluated. The follow-up …

Benign tumors of the liver

EM Brunt - Clinics in Liver Disease, 2001 - liver.theclinics.com
Benign tumors and tumorlike masses of the adult liver include a variety of neoplastic and
regenerative proliferative processes. The lesions of epithelial origin include hepatocellular …

Hepatic neoformations

HW Altmann - Pathology-Research and Practice, 1994 - Elsevier
The aim of the paper is an accurate histologic description and illustration of thoseliver
lesions that are usally summarized under the heading of “hepatic tumors and related …