Helicobacter pylori and Gastric Cancer: Factors That Modulate Disease Risk

LE Wroblewski, RM Peek Jr… - Clinical microbiology …, 2010 - Am Soc Microbiol
Helicobacter pylori is a gastric pathogen that colonizes approximately 50% of the world's
population. Infection with H. pylori causes chronic inflammation and significantly increases …

Systematic review of the epidemiology of complicated peptic ulcer disease: incidence, recurrence, risk factors and mortality

JY Lau, J Sung, C Hill, C Henderson, CW Howden… - Digestion, 2011 - karger.com
Abstract Background/Aims: The incidence of uncomplicated peptic ulcer has decreased in
recent years. It is unclear what the impact of this has been on the epidemiology of peptic …

Helicobacter pylori Infection

KEL McColl - New England Journal of Medicine, 2010 - Mass Medical Soc
A 29-year-old man presents with intermittent epigastric discomfort, without weight loss or
evidence of gastrointestinal bleeding. He reports no use of aspirin or nonsteroidal …

The global health burden of infection‐associated cancers in the year 2002

DM Parkin - International journal of cancer, 2006 - Wiley Online Library
Several infectious agents are considered to be causes of cancer in humans. The fraction of
the different types of cancer, and of all cancers worldwide and in different regions, has been …

Helicobacter pylori and gastrointestinal tract adenocarcinomas

RM Peek Jr, MJ Blaser - Nature Reviews Cancer, 2002 - nature.com
Although gastric adenocarcinoma is associated with the presence of Helicobacter pylori in
the stomach, only a small fraction of colonized individuals develop this common malignancy …

American College of Gastroenterology guideline on the management of Helicobacter pylori infection

WD Chey, BCY Wong… - Official journal of the …, 2007 - journals.lww.com
Helicobacter pylori (H. pylori) remains a prevalent, worldwide, chronic infection. Though the
prevalence of this infection appears to be decreasing in many parts of the world, H. pylori …

Environmental and genetic risk factors for gastric cancer

D Shah, D Bentrem - Journal of surgical oncology, 2022 - Wiley Online Library
Gastric cancer is a heterogeneous and prevalent disease. The traditional environmental
exposures associated with an elevated risk of gastric cancer are less prevalent in the United …

[HTML][HTML] Infection with Helicobacter pylori

IARC Working Group on the Evaluation of … - … , liver flukes and …, 1994 - ncbi.nlm.nih.gov
The presence of spiral-shaped bacteria on human gastric mucosa was first recognized
nearly one hundred years ago (Pel, 1899). These bacteria were isolated for the first time in …

Persistent bacterial infections: the interface of the pathogen and the host immune system

DM Monack, A Mueller, S Falkow - Nature Reviews Microbiology, 2004 - nature.com
Persistent bacterial infections involving Mycobacterium tuberculosis, Salmonella enterica
serovar Typhi (S. typhi) and Helicobacter pylori pose significant public-health problems …

Changing epidemiology and etiology of upper and lower gastrointestinal bleeding

K Oakland - Best practice & research Clinical gastroenterology, 2019 - Elsevier
Upper gastrointestinal bleeding (UGIB) develops in the oesophagus, stomach or duodenum
and has an incidence of 47/100,000. Lower GIB (LGIB) develops in the small bowel, colon or …