Tumor cell migration is affected by the aryl hydrocarbon receptor (AhR). However, the
systematic molecular mechanisms underlying AhR-mediated migration of human …

Tumours can escape the immune system by expressing programmed death-ligand-1 (PD-
L1), which allows them to bind to PD-1 on T-cells and avoid recognition by the immune …

Abstract Indoleamine 2, 3 dioxygenase (IDO) is upregulated in many tumor types, including
breast cancer, and plays a reputable role in promoting tumor immune tolerance. The …

Primary brain tumors, both malignant and benign, are diagnosed in adults at an incidence
rate of approximately 23 people per 100 thousand. The role of AhR in carcinogenesis has …

The aryl hydrocarbon receptor (AHR) is a ligand-activated transcription factor that responds
to a wide range of chemicals, including chemical carcinogens such as dioxins and …

Aryl hydrocarbon receptor (AHR) is a transcription factor that regulates the activity of multiple
innate and adaptive immune cells subsequent to binding to numerous endogenous and …

Leishmaniasis is a parasitic disease that is prevalent in 90 countries, and yet no licensed
human vaccine exists against it. Toward control of leishmaniasis, we have developed …

Introduction The activation of the kynurenine pathway in cancer progression and metastasis
through immunomodulatory pathways has drawn attention to the potential for kynurenine …

Reactive oxygen species (ROS) are by-products of metabolism of oxygen and they play an
important role in normal homeostasis and cell signaling, as well as in the initiation of …

Aryl hydrocarbon receptor (AHR) is a ligand‑activated transcription factor, whose canonical
pathway mainly regulates the genes involved in xenobiotic metabolism. However, it can also …