Targeting ferroptosis in gastric cancer: Strategies and opportunities

J Le, G Pan, C Zhang, Y Chen, AK Tiwari… - Immunological …, 2024 - Wiley Online Library
Ferroptosis is a novel form of programmed cell death morphologically, genetically, and
biochemically distinct from other cell death pathways and characterized by the accumulation …

[HTML][HTML] The mechanisms of ferroptosis and its role in atherosclerosis

X Xu, XD Xu, MQ Ma, Y Liang, YB Cai, ZX Zhu… - Biomedicine & …, 2024 - Elsevier
Ferroptosis is a newly identified form of non-apoptotic programmed cell death, characterized
by the iron-dependent accumulation of lethal lipid reactive oxygen species (ROS) and …

Bone-targeting exosome nanoparticles activate Keap1/Nrf2/GPX4 signaling pathway to induce ferroptosis in osteosarcoma cells

W Chen, Z Li, N Yu, L Zhang, H Li, Y Chen… - Journal of …, 2023 - Springer
Background In recent years, the development of BMSCs-derived exosomes (EXO) for the
treatment of osteosarcoma (OS) is a safe and promising modality for OS treatment, which …

Ferrostatin-1 improves neurological impairment induced by ischemia/reperfusion injury in the spinal cord through ERK1/2/SP1/GPX4

S Liu, F Chen, J Han, L Wang, Y Dong - Experimental Neurology, 2024 - Elsevier
Spinal cord ischemia/reperfusion injury (SCIRI) induced by artificial aortic occlusion for a
while during aortic surgery is a serious complication, leading to paraplegia and even death …

Overcoming ROS Resistance of Photodynamic Therapy with Self‐Assembled Nano‐Prodrugs for Efficient Triple‐Negative Breast Cancer

B Li, J Tian, X Xie, F Zhang, C Wu… - Advanced Functional …, 2024 - Wiley Online Library
Triple‐negative breast cancer (TNBC) is endowed with a highly aggressive nature that
results in distant metastases and high recurrence rates, yet limited success is realized in …

Apigenin-7-glucoside-loaded nanoparticle alleviates intestinal ischemia-reperfusion by ATF3/SLC7A11-mediated ferroptosis

X Zhao, Z Wang, G Wu, L Yin, L Xu, N Wang… - Journal of Controlled …, 2024 - Elsevier
Intestinal ischemia reperfusion injury (II/R injury) is a common and intractable
pathophysiological process in critical patients, for which exploring new treatments and …

Biomimetic nanoarchitectonics with chitosan nanogels for collaborative induction of ferroptosis and anticancer immunity for cancer therapy

N Yang, X Pan, X Zhou, Z Liu, J Yang… - Advanced …, 2024 - Wiley Online Library
Immunogenic cell death (ICD) shows promising therapeutic potential for tumor regression.
However, the low sensitivity and immunosuppressive state of current cell death manners …

Ferroptosis: Potential opportunities for natural products in cancer therapy

A Nie, C Shen, Z Zhou, J Wang, B Sun… - Phytotherapy …, 2024 - Wiley Online Library
Cancer cells often exhibit defects in the execution of cell death, resulting in poor clinical
outcomes for patients with many cancer types. Ferroptosis is a newly discovered form of …

A multifunctional liposome for synergistic chemotherapy with ferroptosis activation of Triple-negative breast Cancer

J Chai, J Hu, T Wang, X Bao, J Luan… - Molecular …, 2023 - ACS Publications
There is an urgent need to develop efficient treatments for highly invasive triple-negative
breast cancer (TNBC) with a high rate of postoperative. Baicalin (BA) has shown inhibitory …

Biogenic selenium nanoparticles synthesized with alginate oligosaccharides alleviate heat stress-induced oxidative damage to organs in broilers through activating …

XQ Ye, YR Zhu, YY Yang, SJ Qiu, WC Liu - Antioxidants, 2023 - mdpi.com
Selenium (Se) is an essential trace element for maintaining health due to its ideal
antioxidant properties. We previously prepared a new type of biogenic selenium …