[HTML][HTML] Visnagin attenuates acute pancreatitis via Nrf2/NFκB pathway and abrogates associated multiple organ dysfunction

LP Pasari, A Khurana, P Anchi, MA Saifi… - Biomedicine & …, 2019 - Elsevier
Acute pancreatitis (AP) is an exocrine dysfunction of the pancreas where oxidative stress
and inflammatory cytokines play a key role in induction and progression of the disease …

Nanoceria for ocular diseases: recent advances and future prospects

W Cui, Y Wang, C Luo, J Xu, K Wang, H Han… - Materials Today Nano, 2022 - Elsevier
Nanoceria, well known as a type of nanozyme, exhibits unique auto-regenerative
antioxidant capacity, mainly originating from a fraction of Ce 3+ ions that can be reversibly …

Rare earth cerium oxide nanoparticles attenuated liver fibrosis in bile duct ligation mice model

C Godugu, A Khurana, MA Saifi - Journal of Trace Elements in Medicine …, 2023 - Elsevier
Liver fibrosis is one of the major liver complications which eventually progresses to liver
cirrhosis and liver failure. Cerium oxide nanoparticles, also known as nanoceria (NC) are …

Superoxide dismutase mimetic nanoceria restrains cerulein induced acute pancreatitis

A Khurana, P Anchi, P Allawadhi, V Kumar… - …, 2019 - Taylor & Francis
Aim: The present study was carried out to assess the effect of nanoceria (NC) on pancreatic
inflammation caused by cerulein. Methods: NC was characterized and in vitro studies were …

[HTML][HTML] Ameliorative effects and mechanism of crocetin in arsenic trioxide‑induced cardiotoxicity in rats

Z Zhao, J Li, B Zheng, Y Liang… - Molecular …, 2020 - spandidos-publications.com
Arsenic trioxide (ATO) is commonly used to treat patients with acute promyelocytic leukemia
since it was authorized by the US Food and Drug Administration in the 1970s, but its …

Yttrium oxide nanoparticles reduce the severity of acute pancreatitis caused by cerulein hyperstimulation

A Khurana, P Anchi, P Allawadhi, V Kumar… - … , Biology and Medicine, 2019 - Elsevier
Oxidative stress plays a major role in acute pancreatitis (AP), leading to massive
macrophage infiltration. Nanoyttria (NY) possesses potent free radical scavenging activity …

Nimbolide ameliorates unilateral ureteral obstruction-induced renal fibrosis by inhibition of TGF-β and EMT/Slug signalling

S Annaldas, MA Saifi, A Khurana, C Godugu - Molecular immunology, 2019 - Elsevier
Chronic kidney disease (CKD) involves interstitial fibrosis as an underlying pathological
process associated with compromised renal function irrespective of etiological cause of the …

Tropolone derivative hinokitiol ameliorates cerulein-induced acute pancreatitis in mice

Y Chelpuri, S Pabbathi, GR Alla, RK Yadala… - International …, 2022 - Elsevier
Hinokitiol is a natural bio-active tropolone derivative with promising antioxidant and anti-
inflammatory properties. This study was conducted to evaluate the ameliorative effects of …

Synthesis of silymarin− selenium nanoparticle conjugate and examination of its biological activity in vitro

S Staroverov, S Kozlov, A Fomin, K Gabalov… - ADMET and …, 2021 - hrcak.srce.hr
Sažetak Silymarin (Sil) was conjugated to selenium nanoparticles (SeNPs) to increase Sil
bioavailability. The conjugates were monodisperse; the average diameter of the native …

Withaferin A, a novel compound of Indian ginseng (Withania somnifera), ameliorates Cerulein‐induced acute pancreatitis: Possible role of oxidative stress and …

VL Tiruveedi, S Bale, A Khurana… - Phytotherapy …, 2018 - Wiley Online Library
Acute pancreatitis is an inflammatory disorder of the pancreas that may precipitate due to
various reasons such as chronic alcoholism, gall stone obstruction, and life style. Current …