1, 25-Dihyroxyvitamin D3 promotes FOXP3 expression via binding to vitamin D response elements in its conserved noncoding sequence region

SW Kang, SH Kim, N Lee, WW Lee… - The Journal of …, 2012 - journals.aai.org
FOXP3-positive regulatory T (Treg) cells are a unique subset of T cells with immune
regulatory properties. Treg cells can be induced from non-Treg CD4+ T cells (induced Treg …

Environmental and gene-environment interactions and risk of rheumatoid arthritis

EW Karlson, K Deane - Rheumatic Disease Clinics of North America, 2012 - Elsevier
Multiple environmental factors including hormones, dietary factors, infections, and exposure
to tobacco smoke, as well as gene-environment interactions, have been associated with …

Vitamin D and its role during pregnancy in attaining optimal health of mother and fetus

CL Wagner, SN Taylor, A Dawodu, DD Johnson… - Nutrients, 2012 - mdpi.com
Despite its discovery a hundred years ago, vitamin D has emerged as one of the most
controversial nutrients and prohormones of the 21st century. Its role in calcium metabolism …

Vitamin D in systemic lupus erythematosus: modest association with disease activity and the urine protein‐to‐creatinine ratio

M Petri, KJ Bello, H Fang, LS Magder - Arthritis & Rheumatism, 2013 - Wiley Online Library
Objective To investigate whether an increase in vitamin D levels in patients with systemic
lupus erythematosus (SLE) was associated with improvement in disease activity. Methods A …

A novel hypothesis for COVID-19 pathogenesis: Retinol depletion and retinoid signaling disorder

AR Sarohan, M Kızıl, AÇ İnkaya, S Mahmud, M Akram… - Cellular signalling, 2021 - Elsevier
The SARS-CoV-2 virus has caused a worldwide COVID-19 pandemic. In less than a year
and a half, more than 200 million people have been infected and more than four million …

The role of vitamin D in melanogenesis with an emphasis on vitiligo

K AlGhamdi, A Kumar, N Moussa - Indian Journal of Dermatology …, 2013 - ijdvl.com
Vitiligo is a common pigmentary disorder caused by the destruction of functional
melanocytes. Vitamin D is an essential hormone synthesized in the skin and is responsible …

Vitamin D deficiency in alopecia areata

A Aksu Cerman, S Sarikaya Solak… - British Journal of …, 2014 - academic.oup.com
Background Alopecia areata (AA) is a T cell‐mediated autoimmune disease that causes
inflammation around anagen‐stage hair follicles. Insufficient levels of vitamin D have been …

Prevalence of vitamin D deficiency and its relationship with thyroid autoimmunity in Asian Indians: a community-based survey

R Goswami, RK Marwaha, N Gupta… - British Journal of …, 2009 - cambridge.org
25-Hydroxy vitamin D (25 (OH) D) deficiency is linked with predisposition to autoimmune
type 1 diabetes and multiple sclerosis. Our objective was to assess the relationship between …

Hygiene hypothesis and autoimmune diseases: A narrative review of clinical evidences and mechanisms

G Murdaca, M Greco, M Borro, S Gangemi - Autoimmunity Reviews, 2021 - Elsevier
Since the start of the “modern era”, characterized by the increase in urbanization, a
progressive attention to hygiene and autoimmune conditions has considerably grown …

Vitamin D, immunity and lupus

M Cutolo, K Otsa - lupus, 2008 - journals.sagepub.com
The identification of vitamin D receptor in cells involved in the immune response and the
discovery that activated dendritic cells produce vitamin D hormone suggested that vitamin D …