Origin of antibiotics and antibiotic resistance, and their impacts on drug development: A narrative review

G Muteeb, MT Rehman, M Shahwan, M Aatif - Pharmaceuticals, 2023 - mdpi.com
Antibiotics have revolutionized medicine, saving countless lives since their discovery in the
early 20th century. However, the origin of antibiotics is now overshadowed by the alarming …

Pneumocystis jirovecii pneumonia in people living with HIV: a review

EG McDonald, A Afshar, B Assiri, T Boyles… - Clinical Microbiology …, 2024 - Am Soc Microbiol
Pneumocystis jirovecii is a ubiquitous opportunistic fungus that can cause life-threatening
pneumonia. People with HIV (PWH) who have low CD4 counts are one of the populations at …

Which trial do we need? Combination treatment of Pneumocystis jirovecii pneumonia in non-HIV infected patients

P Koehler, J Prattes, M Simon, L Haensel… - Clinical Microbiology …, 2023 - Elsevier
Pneumocystis jirovecii pneumonia (PJP) is an increasingly prevalent, opportunistic, and life-
threatening fungal infection [1]. In recent years a rising incidence in immunocompromised …

Novel 1, 2, 3-triazole-sulphadiazine-ZnO hybrids as potent antimicrobial agents against carbapenem resistant bacteria

FS Aljohani, N Rezki, MR Aouad, M Hagar, BA Bakr… - Antibiotics, 2022 - mdpi.com
Bacterial pneumonia is considered one of the most virulent diseases with high morbidity and
mortality rates, especially in hospitalized patients. Moreover, bacterial resistance increased …

Anti-tumor activity of trimethoprim-sulfamethoxazole against melanoma skin cancer through triggering allergic reaction and promoting immunity

HY Kim, HG Kang, HM Kim, HJ Jeong - International Immunopharmacology, 2023 - Elsevier
The anti-cancer impact of an allergic reaction is strongly linked to immunity enhancement.
Trimethoprim-sulfamethoxazole (TMP-SMX), an antibiotic, has potential immunomodulatory …

The interaction between cucurbit [7] uril and trimethoprim and its effect on the properties of trimethoprim

L Zhang, L Wang, X Zhao, X Wang, Z Tao… - Journal of Molecular …, 2023 - Elsevier
Trimethoprim (TMP) is a broad-spectrum antibacterial agent that exhibits an obvious
synergistic effect when used in combination with sulfa antibiotics, but its poor solubility and …

Pneumocystis jirovecii in solid organ transplant recipients: updates in epidemiology, diagnosis, treatment, and prevention

T Saadatzadeh, M Angarone… - Current Opinion in …, 2024 - journals.lww.com
Pneumocystis jirovecii in solid organ transplant recipients:... : Current Opinion in Infectious
Diseases Pneumocystis jirovecii in solid organ transplant recipients: updates in epidemiology …

Features and global impact of invasive fungal infections caused by Pneumocystis jirovecii: A systematic review to inform the World Health Organization fungal priority …

B McMullan, HY Kim, A Alastruey-Izquierdo… - Medical …, 2024 - academic.oup.com
This systematic review evaluates the current global impact of invasive infections caused by
Pneumocystis jirovecii (principally pneumonia: PJP), and was carried out to inform the World …

Re:'Which trial do we need? Combination treatment of Pneumocystis jirovecii pneumonia in non-HIV infected patients' by Cornely et al.

G Desoubeaux, A Lemaignen… - Clinical …, 2023 - clinicalmicrobiologyandinfection …
We read with great interest the article written by Koehler et al.[1] published in Clin Microbiol
Infect. We totally agree with the necessity to implement additional clinical trials to assess the …

[PDF][PDF] Separation and determination of sulfamethoxazole, trimethoprim and metoclopramide hydrochloride by RP-HPLC method in pure and in Pharmaceutical …

AL Azeez, SAH Al-Ameri, AS Mahdi… - History of Medicine, 2023 - researchgate.net
A very accurate, fast and simple method for separating and determine pharmaceutical
compounds sulfamethoxazole (Sulfa), trimethoprim (Tri), and metacalpermide hydrochloride …