Extracellular nucleotides, cartilage stress, and calcium crystal formation

RD Graff, M Picher, GM Lee - Current opinion in rheumatology, 2003 - journals.lww.com
Nucleotides are released by chondrocytes at rest and in response to mechanical stimulation.
Extracellular nucleotides are metabolized by a variety of ectoenzymes, producing free …

Vitamin D3 prevents the increase in ectonucleotidase activities and ameliorates lipid profile in type 1 diabetic rats

NS Calgaroto, P Da Costa, AM Cardoso… - Molecular and Cellular …, 2015 - Springer
This study was designed to assess the potential effect of vitamin D 3 (VD 3) in avoiding
atherothrombosis by modulation of lipid metabolism and platelet activation in type 1 diabetic …

The cannabinoid 2 receptor as a potential therapeutic target for sepsis

K Richard Kasten, J Tschop… - … Metabolic & Immune …, 2010 - ingentaconnect.com
The sepsis syndrome represents an improper immune response to pathogens and is
associated with an unacceptably high rate of mortality. Although supportive care is of benefit …

C-terminal splicing of NTPDase2 provides distinctive catalytic properties, cellular distribution and enzyme regulation

CJH Wang, SM Vlajkovic, GD Housley… - Biochemical …, 2005 - portlandpress.com
The present study provides functional characterization of alternative splicing of the
NTPDase2 (ecto-nucleoside triphosphate diphosphohydrolase-2) involved in the regulation …

Purinergic signaling in glioma progression

E Braganhol, MR Wink, G Lenz, AMO Battastini - Glioma signaling, 2013 - Springer
Among the pathological alterations that give tumor cells invasive potential, purinergic
signaling is emerging as an important component. Studies performed in in vitro, in vivo and …

The nucleoside triphosphate diphosphohydrolase-1/CD39 is incorporated into human immunodeficiency type 1 particles, where it remains biologically active

C Barat, G Martin, AR Beaudoin, J Sévigny… - Journal of molecular …, 2007 - Elsevier
Human immunodeficiency virus type 1 (HIV-1) carries a variety of host proteins in addition to
virus-encoded structural proteins, both in its envelope and inside the viral particle. Previous …

Extracellular interaction between hCD98 and the PDZ class II domain of hCASK in intestinal epithelia

Y Yan, S Vasudevan, H Nguyen, U Bork… - Journal of Membrane …, 2007 - Springer
The extracellular domain of the glycoprotein-associated integrin hCD98 protrudes into the
basolateral extracellular space of the intestine and contains a PDZ class II-binding domain …

Regulation of [3H]MPP+ transport by phosphorylation/dephosphorylation pathways in RBE4 cells: role of ecto-alkaline phosphatase

C Calhau, F Martel, P Soares-da-Silva… - Naunyn-Schmiedeberg's …, 2002 - Springer
The aim of this study was to investigate the role of phosphorylation/dephosphorylation
mechanisms at the blood-brain barrier (BBB) in the uptake of organic cations. The …

Marmoset fine B cell and T cell epitope specificities mapped onto a homology model of the extracellular domain of human myelin oligodendrocyte glycoprotein

MF Mesleh, N Belmar, CW Lu, VV Krishnan… - Neurobiology of …, 2002 - Elsevier
Aberrant association of autoantibodies with myelin oligodendrocyte glycoprotein (MOG), an
integral membrane protein of the central nervous system (CNS) myelin, has been implicated …

Increase of Fas-induced apoptosis by inhibition of extracellular phosphorylation of Fas receptor in Jurkat cell line

C Lautrette*, E Loum-Ribot, D Petit… - Apoptosis, 2006 - Springer
Apoptosis signalling through the Fas pathway requires several steps of aggregation of the
Fas receptor in the membrane, including aggregation that may occur in the absence of Fas …