[HTML][HTML] An overview of drug resistance in protozoal diseases

R Capela, R Moreira, F Lopes - International journal of molecular …, 2019 - mdpi.com
Protozoan diseases continue to be a worldwide social and economic health problem.
Increased drug resistance, emerging cross resistance, and lack of new drugs with novel …

[HTML][HTML] Artemisinin-based combination therapy (ACT) and drug resistance molecular markers: A systematic review of clinical studies from two malaria endemic …

A Arya, LPK Foko, S Chaudhry, A Sharma… - International Journal for …, 2021 - Elsevier
Artemisinin-based combination therapies (ACT) are currently used as a first-line malaria
therapy in endemic countries worldwide. This systematic review aims at presenting the …

Delftia tsuruhatensis TC1 symbiont suppresses malaria transmission by anopheline mosquitoes

W Huang, J Rodrigues, E Bilgo, JR Tormo… - Science, 2023 - science.org
Malaria control demands the development of a wide range of complementary strategies. We
describe the properties of a naturally occurring, non–genetically modified symbiotic …

[HTML][HTML] Promising nanomaterials in the fight against malaria

LN Borgheti-Cardoso, M San Anselmo… - Journal of Materials …, 2020 - pubs.rsc.org
For more than one hundred years, several treatments against malaria have been proposed
but they have systematically failed, mainly due to the occurrence of drug resistance in part …

The development process for discovery and clinical advancement of modern antimalarials

TD Ashton, SM Devine, JJ Mohrle, B Laleu… - Journal of Medicinal …, 2019 - ACS Publications
Malaria is a devastating disease caused by Plasmodium parasites, resulting in
approximately 435000 deaths in 2018. The impact of malaria is compounded by the …

[HTML][HTML] Global trend of Plasmodium malariae and Plasmodium ovale spp. malaria infections in the last two decades (2000–2020): a systematic review and meta …

J Hawadak, RR Dongang Nana, V Singh - Parasites & vectors, 2021 - Springer
Background Recent studies indicate that the prevalence of non-falciparum malaria,
including Plasmodium malariae and Plasmodium ovale spp., is increasing, with some …

[HTML][HTML] Genetic diversity and drug resistance surveillance of Plasmodium falciparum for malaria elimination: is there an ideal tool for resource-limited sub-Saharan …

TO Apinjoh, A Ouattara, VPK Titanji, A Djimde… - Malaria journal, 2019 - Springer
The intensification of malaria control interventions has resulted in its global decline, but it
remains a significant public health burden especially in sub-Saharan Africa (sSA) …

[HTML][HTML] Current challenges and nanotechnology-based pharmaceutical strategies for the treatment and control of malaria

L Gujjari, H Kalani, SK Pindiprolu… - Parasite Epidemiology …, 2022 - Elsevier
Malaria is one of the prevalent tropical diseases caused by the parasitic protozoan of the
genus Plasmodium spp. With an estimated 228 million cases, it is a major public health …

New structural classes of antimalarials

GK Rathod, M Jain, KK Sharma, S Das, A Basak… - European journal of …, 2022 - Elsevier
Malaria remains a major vector borne disease claiming millions of lives worldwide due to
infections caused by Plasmodium sp. Discovery and development of antimalarial drugs have …

In silico Structure Prediction, Molecular Docking, and Dynamic Simulation of Plasmodium falciparum AP2-I Transcription Factor

DO Oladejo, GO Oduselu… - … and Biology Insights, 2023 - journals.sagepub.com
Plasmodium falciparum Apicomplexan Apetala 2 Invasion (Pf AP2-I) transcription factor (TF)
is a protein that regulates the expression of a subset of gene families involved in P …