Macroscopic cerebral tumor growth modeling from medical images: A review

A Elazab, YM Abdulazeem, AM Anter, Q Hu… - IEEE …, 2018 - ieeexplore.ieee.org
Mathematical models have been ubiquitously employed in various applications. One of
these applications that arose in the past few decades is cerebral tumor growth modeling …

[HTML][HTML] A note on the numerical approach for the reaction–diffusion problem to model the density of the tumor growth dynamics

E Özuğurlu - Computers & Mathematics with Applications, 2015 - Elsevier
In this article, we numerically solve an equation modeling the evolution of the density of
glioma in the brain—the most malignant form of brain tumor quantified in terms of net rates of …

An adaptive semi‐implicit finite element solver for brain cancer progression modeling

K Tzirakis, CP Papanikas, V Sakkalis… - International Journal …, 2023 - Wiley Online Library
Glioblastoma is the most aggressive and infiltrative glioma, classified as Grade IV, with the
poorest survival rate among patients. Accurate and rigorously tested mechanistic in silico …

Simulating radiotherapy effect in high‐grade glioma by using diffusive modeling and brain atlases

A Roniotis, K Marias, V Sakkalis… - BioMed Research …, 2012 - Wiley Online Library
Applying diffusive models for simulating the spatiotemporal change of concentration of
tumour cells is a modern application of predictive oncology. Diffusive models are used for …

The influence of anisotropy on the clinical target volume of brain tumor patients

G Buti, A Ajdari, K Hochreuter, H Shih… - Physics in Medicine …, 2024 - iopscience.iop.org
Objective. Current radiotherapy guidelines for glioma target volume definition recommend a
uniform margin expansion from the gross tumor volume (GTV) to the clinical target volume …

Web-based workflow planning platform supporting the design and execution of complex multiscale cancer models

V Sakkalis, S Sfakianakis, E Tzamali… - IEEE Journal of …, 2014 - ieeexplore.ieee.org
Significant Virtual Physiological Human efforts and projects have been concerned with
cancer modeling, especially in the European Commission Seventh Framework research …

[HTML][HTML] Exploring the competition between proliferative and invasive cancer phenotypes in a continuous spatial model

E Tzamali, G Grekas, K Marias, V Sakkalis - PLoS One, 2014 - journals.plos.org
Tumor is characterized by extensive heterogeneity with respect to its microenvironment and
its genetic composition. We extend a previously developed monoclonal continuous spatial …

Automated detection of glioblastoma tumor in brain magnetic imaging using ANFIS classifier

P Thirumurugan, D Ramkumar, K Batri… - … Journal of Imaging …, 2016 - Wiley Online Library
This article proposes a novel and efficient methodology for the detection of Glioblastoma
tumor in brain MRI images. The proposed method consists of the following stages as …

A proposed paradigm shift in initializing cancer predictive models with DCE-MRI based PK parameters: A feasibility study

A Roniotis, ME Oraiopoulou, E Tzamali… - Cancer …, 2015 - journals.sagepub.com
Glioblastoma multiforme is the most aggressive type of glioma and the most common
malignant primary intra-axial brain tumor. In an effort to predict the evolution of the disease …

Glioma growth modeling based on the effect of vital nutrients and metabolic products

M Papadogiorgaki, P Koliou, ME Zervakis - Medical & Biological …, 2018 - Springer
Glioma brain tumors exhibit considerably aggressive behavior leading to high mortality
rates. Mathematical modeling of tumor growth aims to explore the interactions between …