The recommendations listed in this document are, whenever possible, evidence based. An
extensive evidence review was conducted for the period beginning March 2008 through …

Hypertension is characterized by structural and functional changes in blood vessels that
travel with increased arterial stiffness, vascular inflammation, and endothelial dysfunction …

Background Blood pressure lowering is an established strategy for preventing microvascular
and macrovascular complications of diabetes, but its role in the prevention of diabetes itself …

Background: Reliable quantification of the association between blood pressure (BP) and risk
of type 2 diabetes is lacking. Objectives: This study sought to determine the association …

Abstract Angiotensin II (Ang II) increases adhesion molecules, cytokines and chemokines
and exerts a proinflammatory effect on leucocytes, endothelial cells and vascular smooth …

Abstract C-reactive protein (CRP), the prototypical acute-phase reactant, is one of the most
widely known biomarkers of cardiovascular disease. Circulating levels of CRP are clinically …

Background—Data supporting the prognostic significance of high-sensitivity C-reactive
protein (hs-CRP) are derived largely from individuals with no overt coronary artery disease …

More than 80% of patients with type 2 diabetes mellitus develop hypertension, and approx.
20% of patients with hypertension develop diabetes. This combination of cardiovascular risk …

Background and Objective RESPIRE, a randomized trial of an improved cookstove, was
conducted in Guatemala to assess health effects of long-term reductions in wood smoke …

Background Prior evidence suggests a link between inflammation and hypertension.
Interleukin-6 (IL-6) has been implicated in animal studies to play an important role in …