Systematic review and meta-analysis of human genetic variants contributing to COVID-19 susceptibility and severity

K Gupta, G Kaur, T Pathak, I Banerjee - Gene, 2022 - Elsevier
The COVID-19 pandemic has spawned global health crisis of unprecedented magnitude,
claiming millions of lives and pushing healthcare systems in many countries to the brink …

[HTML][HTML] mRNA expression of toll-like receptors 3, 7, 8, and 9 in the nasopharyngeal epithelial cells of coronavirus disease 2019 patients

Z Bagheri-Hosseinabadi, E Rezazadeh Zarandi… - BMC infectious …, 2022 - Springer
Background The etiopathogenesis of coronavirus disease 2019 (COVID-19) stem partially
from the abnormal activation of the innate and adaptive immune systems. Here in the current …

The SARS-CoV-2 spike S1 protein induces global proteomic changes in ATII-like rat L2 cells that are attenuated by hyaluronan

JA Mobley, A Molyvdas, K Kojima… - … of Physiology-Lung …, 2023 - journals.physiology.org
The COVID-19 pandemic continues to impose a major impact on global health and economy
since its identification in early 2020, causing significant morbidity and mortality worldwide …

[HTML][HTML] The single nucleotide polymorphism rs4986790 (c.896A>G) in the gene TLR4 as a protective factor in corona virus disease 2019 (COVID-19)

C Zacher, K Schönfelder, H Rohn, W Siffert… - Frontiers in …, 2024 - frontiersin.org
Background and aims Several factors, such as hypertension and diabetes mellitus, are
known to influence the course of coronavirus disease 2019 (COVID-19). However, there is …

Interferon-Induced Transmembrane Protein-3 Rs12252-G Variant Increases COVID-19 Mortality Potential in Egyptian Population

SM Elessawy, A Shehab, DA Soliman, MA Eldeeb… - Viral …, 2024 - liebertpub.com
Coronavirus disease 2019 (COVID-19) represented an international health risk. Variants of
the interferon-induced transmembrane protein-3 (IFITM3) gene can increase the risk of …

[HTML][HTML] Variant rs4986790 of toll-like receptor 4 affects the signaling and induces cell dysfunction in patients with severe COVID-19

J Flores-Gonzalez, L Chavez-Galan… - International Journal of …, 2024 - Elsevier
Objectives We investigated the expression of toll-like receptor (TLR)-4 on the cell surface of
innate and adaptive cells from patients with COVID-19 carrying the rs4986790 GG genotype …