The extracellular matrix (ECM) is a fundamental component of multicellular organisms that provides mechanical and chemical cues that orchestrate cellular and tissue organization …
I Letunic, P Bork - Nucleic acids research, 2018 - academic.oup.com
Abstract SMART (Simple Modular Architecture Research Tool) is a web resource (http://smart. embl. de) for the identification and annotation of protein domains and the …
N 6-methyladenosine (m6A) is the most abundant internal modification of eukaryotic messenger RNA (mRNA) and plays critical roles in RNA biology. The function of this …
Abstract NCBI's Conserved Domain Database (CDD) aims at annotating biomolecular sequences with the location of evolutionarily conserved protein domain footprints, and …
Abstract InterPro (http://www. ebi. ac. uk/interpro/) is a freely available database used to classify protein sequences into families and to predict the presence of important domains …
K Zaremba-Niedzwiedzka, EF Caceres, JH Saw… - Nature, 2017 - nature.com
The origin and cellular complexity of eukaryotes represent a major enigma in biology. Current data support scenarios in which an archaeal host cell and an alphaproteobacterial …
In eukaryotic cells, diverse stresses trigger coalescence of RNA-binding proteins into stress granules. In vitro, stress-granule-associated proteins can demix to form liquids, hydrogels …
M Borowiak, J Fischer, JA Hammerl… - Journal of …, 2017 - academic.oup.com
Objectives Plasmid-mediated mobilized colistin resistance is currently known to be caused by phosphoethanolamine transferases termed MCR-1, MCR-2, MCR-3 and MCR-4 …
Abstract eggNOG is a public resource that provides Orthologous Groups (OGs) of proteins at different taxonomic levels, each with integrated and summarized functional annotations …