Specific RNA sequences modified by a methylated adenosine, N 6-methyladenosine (m 6
A), contribute to the post-transcriptional regulation of gene expression. The quantity of m 6 A …

Abstract N 6-methyladenosine (m 6 A) is the most abundant internal modification on
eukaryotic mRNAs. Demethylation of m 6 A on mRNA is catalyzed by the enzyme fat mass …

Myocardial infarction that causes damage to heart muscle can lead to heart failure. The
identification of molecular mechanisms promoting myocardial regeneration represents a …

Metabolites, depicting physiological and pathophysiological state, underpin diverse disease-
associated phenomena. Metabolite detection offers insights for identifying disease …

Atherosclerosis (AS) is an important pathological basis of cardiovascular disease (CVD).
The development of AS commences with endothelial dysfunction due to vascular endothelial …

The post-transcriptional regulation of gene expression plays an important role in heart
development and disease. Cardiac-specific alternative splicing, mediated by RNA-binding …

Background Atherosclerosis (AS) is a critical pathological event during the progression of
cardiovascular diseases. It exhibits fibrofatty lesions on the arterial wall and lacks effective …

M6A methylation is the most prevalent and abundant RNA modification in mammals.
Although there are many studies on the regulatory role of m6A methylation in the immune …

Purpose Chemical modification plays a critical role in regulating human cancer progression,
especially N6-methyladenosine (m6A). However, m6A writer KIAA1429-mediated m6A …

Background: N6-methyladenosine (m6A) methylation is involved in the pathogenesis of
atherosclerosis (AS). Limited studies have examined the role of the m6A methyltransferase …