Survival in a consecutive series of 467 glioblastoma patients: association with prognostic factors and treatment at recurrence at two independent institutions

H Blakstad, J Brekke, MA Rahman, VS Arnesen… - PLoS …, 2023 - journals.plos.org
Therapy of recurrent glioblastoma (GBM) is challenging due to lack of standard treatment.
We investigated physicians' treatment choice at recurrence and prognostic and predictive …

Implementing targeted therapies in the treatment of glioblastoma: previous shortcomings, future promises, and a multimodal strategy recommendation

V Fougner, B Hasselbalch, U Lassen… - Neuro-Oncology …, 2022 - academic.oup.com
The introduction of targeted therapies to the field of oncology has prolonged the survival of
several tumor types. Despite extensive research and numerous trials, similar outcomes have …

Timing of early postoperative MRI following primary glioblastoma surgery—A retrospective study of contrast enhancements in 311 patients

AM Rykkje, VA Larsen, J Skjøth-Rasmussen… - Diagnostics, 2023 - mdpi.com
An early postoperative MRI is recommended following Glioblastoma surgery. This
retrospective, observational study aimed to investigate the timing of an early postoperative …

Prognostic model for predicting overall survival in patients with glioblastoma: an analysis based on the SEER database

Y Luo, L Hao, C Liu, Y Xiang, X Han… - Journal of …, 2023 - journals.sagepub.com
Predicting the prognosis of glioblastoma (GBM) has always been important for improving
survival. An understanding of the prognostic factors for patients with GBM can help guide …

Glioblastoma: A retrospective analysis of the role of the maximal surgical resection on overall survival and progression free survival

G Polonara, D Aiudi, A Iacoangeli, A Raggi… - Biomedicines, 2023 - mdpi.com
Background: Glioblastoma (GBM) is the most common and aggressive primary brain tumor
in adults; despite advances in the understanding of GBM pathogenesis, significant …

Prognostic relevance of radiological findings on early postoperative MRI for 187 consecutive glioblastoma patients receiving standard therapy

AM Rykkje, JF Carlsen, VA Larsen… - Scientific Reports, 2024 - nature.com
Several prognostic factors are known to influence survival for patients treated with IDH-
wildtype glioblastoma, but unknown factors may remain. We aimed to investigate the …

Evidence That a Peptide-Drug/p53 Gene Complex Promotes Cognate Gene Expression and Inhibits the Viability of Glioblastoma Cells

A Neves, T Albuquerque, R Faria, CRA Santos, E Vivès… - Pharmaceutics, 2024 - mdpi.com
Glioblastoma multiform (GBM) is considered the deadliest brain cancer. Conventional
therapies are followed by poor patient survival outcomes, so novel and more efficacious …

Real-World Use of Hypofractionated Radiotherapy for Primary CNS Tumors in the Elderly, and Implications on Medicare Spending

KR Tringale, A Lin, AM Miller, A Khan, L Chen… - Journal of the National …, 2024 - jnccn.org
Background: For elderly patients with high-grade gliomas, 3-week hypofractionated
radiotherapy (HFRT) is noninferior to standard long-course radiotherapy (LCRT). We …

Sequential Evaluation of Hematology Markers as a Prognostic Factor in Glioblastoma Patients

JM Gonçalves, B Carvalho, R Tuna, P Polónia… - Biomedicines, 2024 - mdpi.com
In our study, we investigated the prognostic significance of hematological markers—NLR
(Neutrophil-to-Lymphocyte Ratio), PLR (Platelet-to-Lymphocyte Ratio), and RDW-CV (Red …

Treatment of glioblastoma in Greenlandic patients

S Frandsen, AJ Pedersen, O Gredal… - … of Circumpolar Health, 2023 - Taylor & Francis
ABSTRACT Glioblastoma (GBM), WHO grade IV, is the most common primary malignant
brain tumour among adults with a devastating overall survival of 14–22 months. Standard …