This protocol explains how to perform a fast SCENIC analysis alongside standard best
practices steps on single-cell RNA-sequencing data using software containers and Nextflow …

The mechanisms underlying ribonucleoprotein (RNP) granule assembly, including the basis
for establishing and maintaining RNP granules with distinct composition, are unknown. One …

Acute myeloid leukemia (AML) is a cancer of myeloid-lineage cells with limited therapeutic
options. We previously combined ex vivo drug sensitivity with genomic, transcriptomic, and …

Some patients hospitalized with acute COVID-19 suffer respiratory symptoms that persist for
many months. We delineated the immune-proteomic landscape in the airways and …

Progressive multiple sclerosis (MS) is characterized by unrelenting neurodegeneration,
which causes cumulative disability and is refractory to current treatments. Drug development …

Motivation Estimating microbial association networks from high-throughput sequencing data
is a common exploratory data analysis approach aiming at understanding the complex …

INTRODUCTION Our understanding of the pathophysiology of psychiatric disorders,
including autism spectrum disorder (ASD), schizophrenia (SCZ), and bipolar disorder (BD) …

Plants are essential for life and are extremely diverse organisms with unique molecular
capabilities. Here we present a quantitative atlas of the transcriptomes, proteomes and …

Ferroptosis, a non-apoptotic form of programmed cell death, is triggered by oxidative stress
in cancer, heat stress in plants, and hemorrhagic stroke. A homeostatic transcriptional …

INTRODUCTION Strong genetic associations have been found for a number of psychiatric
disorders. However, understanding the underlying molecular mechanisms remains …