Counterattacking the tick bite: towards a rational design of anti-tick vaccines targeting pathogen transmission

ROM Rego, JJA Trentelman, J Anguita, AM Nijhof… - Parasites & vectors, 2019 - Springer
Hematophagous arthropods are responsible for the transmission of a variety of pathogens
that cause disease in humans and animals. Ticks of the Ixodes ricinus complex are vectors …

Controlling ticks and tick-borne diseases… looking forward

J de la Fuente - Ticks and tick-borne diseases, 2018 - Elsevier
Tick-borne diseases (TBDs) represent a growing burden for human and animal health
worldwide. Several approaches including the use of chemicals with repellency and …

Vaccinomics: A future avenue for vaccine development against emerging pathogens

J de la Fuente, M Contreras - Expert Review of Vaccines, 2021 - Taylor & Francis
Introduction Vaccines are a major achievement in medical sciences, but the development of
more effective vaccines against infectious diseases is essential for prevention and control of …

Quantum vaccinomics platforms to advance in vaccinology

J de la Fuente, M Contreras - Frontiers in Immunology, 2023 - frontiersin.org
The opinion flows from Introduction to the immunological quantum that requires a historical
perspective, to Quantum vaccine algorithms supported by a bibliometric analysis, to …

Prevention of tick-borne diseases: challenge to recent medicine

D Hromníková, D Furka, S Furka, JAD Santana… - Biologia, 2022 - Springer
Ticks represent important vectors and reservoirs of pathogens, causing a number of
diseases in humans and animals, and significant damage to livestock every year. Modern …

Why new vaccines for the control of ectoparasite vectors have not been registered and commercialized?

J de la Fuente, A Estrada-Peña - Vaccines, 2019 - mdpi.com
The prevention and control of vector-borne diseases is a priority for improving global health.
Despite recent advances in the characterization of ectoparasite-host-pathogen molecular …

Vaccination with alpha-Gal protects against mycobacterial infection in the zebrafish model of tuberculosis

I Pacheco, M Contreras, M Villar, MA Risalde, P Alberdi… - Vaccines, 2020 - mdpi.com
The alpha-Gal syndrome (AGS) is associated with tick bites that can induce in humans high
levels of IgE antibodies against the carbohydrate Galα1-3Galβ1-(3) 4GlcNAc-R (α-Gal) …

Universal tick vaccines: candidates and remaining challenges

LF Parizi, NW Githaka, C Logullo, J Zhou, M Onuma… - Animals, 2023 - mdpi.com
Simple Summary Various new technologies have been used to learn more about tick
physiology and biology in hopes of developing vaccines to protect people and animals from …

[HTML][HTML] The Tick Cell Biobank: A global resource for in vitro research on ticks, other arthropods and the pathogens they transmit

L Bell-Sakyi, A Darby, M Baylis… - Ticks and tick-borne …, 2018 - Elsevier
Tick cell lines are increasingly used in many fields of tick and tick-borne disease research.
The Tick Cell Biobank was established in 2009 to facilitate the development and uptake of …

A quantum vaccinomics approach based on protein–protein interactions

M Contreras, S Artigas-Jerónimo… - … Design: Methods and …, 2022 - Springer
Vaccines are the most effective preventive intervention to reduce the impact of infectious
diseases worldwide. In particular, tick-borne diseases represent a growing burden for …