Structural Elucidation and Antiviral Activity of Covalent Cathepsin L Inhibitors

S Falke, J Lieske, A Herrmann, J Loboda… - Journal of Medicinal …, 2024 - ACS Publications
Emerging RNA viruses, including SARS-CoV-2, continue to be a major threat. Cell entry of
SARS-CoV-2 particles via the endosomal pathway involves cysteine cathepsins. Due to …

Harnessing bimetallic iMWA nanosensitizer to unleash ferroptosis and calcium overload: Unlocking tumor vulnerability for potentiated iMWA therapy against …

G Qiu, D Wang, P Xie, Z Li, N Zhou, X Zhang… - Chemical Engineering …, 2024 - Elsevier
Microwave ablation (MWA) holds promise as a tumor treatment modality, yet incomplete
ablation with low-frequency MWA (iMWA) remains a significant obstacle to survival, while …

[PDF][PDF] Potent and selective inhibitory effect of 4-aminoquinoline derivatives on SARS-CoV-2 replication

N Glanzmann, TKF Oliveira, VC de Souza… - … Medicines & Omics, 2024 - researchgate.net
The global coronavirus disease 2019 (COVID-19) pandemic, caused by the highly infectious
severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), had resulted in significant …