β-1 and β-2 adrenoceptors (AR) play a pivotal role in regulation of the activity of the
sympathetic nervous system and agonists and antagonists at both β AR subtypes are …

Although large surveys have documented the favourable safety profile of β 2-adrenoceptor
agonists (β 2-agonists) and, above all, that of the long-acting agents, the presence in the …

Abstract β-Adrenoceptor stimulation serves as the most powerful means to increase cardiac
output in response to stress or exercise. However, sustained β-adrenoceptor stimulation …

Background: Neuraxial blockade is used as primary anesthetic technique in one third of
surgical procedures. The authors tested whether bisoprolol would protect patients at risk for …

Background and Purpose—Cardiac abnormalities occur commonly after subarachnoid
hemorrhage (SAH) and may be caused by excessive release of catecholamines from the …

Numerous studies have demonstrated that β1‐and β2‐adrenergic receptor gene (ADRB1
and ADRB2) variants influence cardiovascular risk and β‐blocker responses in hypertension …

Introduction β-blockers are among the most widely prescribed of all drugs, used for
treatment of a large number of cardiovascular diseases. Herein we evaluate literature …

Abstract β1‐and β2‐Adrenoceptors (AR) play a pivotal role in regulation of the
cardiovascular system. Both β‐AR subtypes are polymorphic. There are two major single …

Aims Extracellular ATP acting on the P2Y11 receptor regulates inflammatory cells. We
hypothesized that polymorphisms in the receptor could influence the risk of acute myocardial …

Objectives Recently, the Arg389Gly β 1-adrenoceptor (β 1 AR) gene polymorphism has
been detected. The Arg variant exhibited increased responsiveness to agonist-induced …