Uncovering near-wall blood flow from sparse data with physics-informed neural networks
Near-wall blood flow and wall shear stress (WSS) regulate major forms of cardiovascular
disease, yet they are challenging to quantify with high fidelity. Patient-specific computational …
disease, yet they are challenging to quantify with high fidelity. Patient-specific computational …
[HTML][HTML] Medical image-based computational fluid dynamics and fluid-structure interaction analysis in vascular diseases
Hemodynamic factors, induced by pulsatile blood flow, play a crucial role in vascular health
and diseases, such as the initiation and progression of atherosclerosis. Computational fluid …
and diseases, such as the initiation and progression of atherosclerosis. Computational fluid …
[HTML][HTML] Design of innovative self-expandable femoral stents using inverse homogenization topology optimization
In this study, we propose a novel computational framework for designing innovative self-
expandable femoral stents. First, a two-dimensional stent unit cell is designed by inverse …
expandable femoral stents. First, a two-dimensional stent unit cell is designed by inverse …
Early atherosclerotic changes in coronary arteries are associated with endothelium shear stress contraction/expansion variability
Although unphysiological wall shear stress (WSS) has become the consensus
hemodynamic mechanism for coronary atherosclerosis, the complex biomechanical stimulus …
hemodynamic mechanism for coronary atherosclerosis, the complex biomechanical stimulus …
[HTML][HTML] On the nonlinear relationship between wall shear stress topology and multi-directionality in coronary atherosclerosis
Abstract Background and Objective In this paper we investigate twelve multi-
directional/topological wall shear stress (WSS) derived metrics and their relationships with …
directional/topological wall shear stress (WSS) derived metrics and their relationships with …
Integrating multi-fidelity blood flow data with reduced-order data assimilation
M Habibi, RM D'Souza, STM Dawson… - Computers in Biology and …, 2021 - Elsevier
High-fidelity patient-specific modeling of cardiovascular flows and hemodynamics is
challenging. Direct blood flow measurement inside the body with in-vivo measurement …
challenging. Direct blood flow measurement inside the body with in-vivo measurement …
[HTML][HTML] Impact of wall displacements on the large-scale flow coherence in ascending aorta
In the context of aortic hemodynamics, uncertainties affecting blood flow simulations hamper
their translational potential as supportive technology in clinics. Computational fluid dynamics …
their translational potential as supportive technology in clinics. Computational fluid dynamics …
Coronary artery stenting affects wall shear stress topological skeleton
C Chiastra, V Mazzi… - Journal of …, 2022 - asmedigitalcollection.asme.org
Despite the important advancements in the stent technology for the treatment of diseased
coronary arteries, major complications still affect the postoperative long-term outcome. The …
coronary arteries, major complications still affect the postoperative long-term outcome. The …
Divergence of the normalized wall shear stress as an effective computational template of low-density lipoprotein polarization at the arterial blood-vessel wall interface
Abstract Background and Objective Near-wall transport of low-density lipoproteins (LDL) in
arteries plays a relevant role in the initiation of atherosclerosis. Although it can be modelled …
arteries plays a relevant role in the initiation of atherosclerosis. Although it can be modelled …
Haemodynamic analysis of branched endografts for complex aortic arch repair
S Sengupta, M Hamady, XY Xu - Bioengineering, 2022 - mdpi.com
This study aims to investigate the haemodynamic response induced by implantation of a
double-branched endograft used in thoracic endovascular aortic repair (TEVAR) of the aortic …
double-branched endograft used in thoracic endovascular aortic repair (TEVAR) of the aortic …