The Hippo pathway is a signalling cascade conserved from Drosophila melanogaster to
mammals. The mammalian core kinase components comprise MST1 and MST2, SAV1 …

Recently, the onset of type 1 diabetes (T1D) has increased rapidly and became a major
public health concern worldwide. Various factors are associated with the development of …

Epithelial transport relies on the proper function and regulation of the tight junction (TJ),
other‐wise uncontrolled paracellular leakage of solutes and water would occur. They also …

The gut is home to our largest collection of microbes. The ability of the immune system to
coevolve with the microbiota during postnatal life allows the host and microbiota to coexist in …

Diverse commensal populations are now regarded as key to physiological homeostasis and
protection against disease. Although bacteria are the most abundant component of …

Classic atopic dermatitis is complicated by asthma, allergic rhinitis, and food allergies,
cumulatively referred to as atopic diseases. Recent discoveries of mutations in the filaggrin …

Oral colon-specific delivery systems emerged as the main therapeutic cargos by making a
significant impact in the field of modern medicine for local drug delivery in intestinal …

Our gut harbours trillions of microorganisms essential for the maintenance of homeostasis
and host physiology in health and disease. In the last decade, there has been a growing …

Redox signalling in the gastrointestinal mucosa is held in an intricate balance. Potent
microbicidal mechanisms can be used by infiltrating immune cells, such as neutrophils, to …

Gut microbial metabolites of polyunsaturated fatty acids have attracted much attention
because of their various physiological properties. Dysfunction of tight junction (TJ) in the …