Biological aspects of selected myokines in skeletal muscle: focus on aging

R Mancinelli, F Checcaglini, F Coscia… - International journal of …, 2021 - mdpi.com
In the last decade, clear evidence has emerged that the cellular components of skeletal
muscle are important sites for the release of proteins and peptides called “myokines” …

Key concepts in muscle regeneration: Muscle “cellular ecology” integrates a gestalt of cellular cross-talk, motility, and activity to remodel structure and restore function

JE Anderson - European journal of applied physiology, 2022 - Springer
This review identifies some key concepts of muscle regeneration, viewed from perspectives
of classical and modern research. Early insights noted the pattern and sequence of …

Deletion of TECRL promotes skeletal muscle repair by up-regulating EGR2

S Geng, SB Liu, W He, X Pan, Y Sun… - Proceedings of the …, 2024 - National Acad Sciences
Myogenic regeneration relies on the proliferation and differentiation of satellite cells. TECRL
(trans-2, 3-enoyl-CoA reductase like) is an endoplasmic reticulum protein only expressed in …

Vitamin d restores skeletal muscle cell remodeling and myogenic program: Potential impact on human health

C Crescioli - International Journal of Molecular Sciences, 2021 - mdpi.com
Skeletal muscle cells, albeit classified as vitamin D receptor (VDR)-poor cells, are finely
controlled by vitamin D through genomic and non-genomic mechanisms. Skeletal muscle …

Satellite cell-specific deletion of Cipc alleviates myopathy in mdx mice

J Zheng, J Lou, Y Li, P Qian, W He, Y Hao, T Xue, Y Li… - Cell Reports, 2022 - cell.com
Skeletal muscle regeneration relies on satellite cells that can proliferate, differentiate, and
form new myofibers upon injury. Emerging evidence suggests that misregulation of satellite …

An Amino Acid Mixture to Counteract Skeletal Muscle Atrophy: Impact on Mitochondrial Bioenergetics

F Bellanti, A Lo Buglio, G Pannone… - International Journal of …, 2024 - mdpi.com
Skeletal muscle atrophy (SMA) is caused by a rise in muscle breakdown and a decline in
protein synthesis, with a consequent loss of mass and function. This study characterized the …

Indicators of increased ER stress and UPR in aged D2-mdx and human dystrophic skeletal muscles

S Krishna, HR Spaulding, JE Koltes… - Frontiers in …, 2023 - frontiersin.org
Duchenne muscular dystrophy (DMD) is a progressive muscle disease that results in muscle
wasting, wheelchair dependence, and eventual death due to cardiac and respiratory …

Bioprocessing Considerations towards the Manufacturing of Therapeutic Skeletal and Smooth Muscle Cells

T Franchi-Mendes, M Silva, AL Cartaxo… - Bioengineering, 2023 - mdpi.com
Tissue engineering approaches within the muscle context represent a promising emerging
field to address the current therapeutic challenges related with multiple pathological …

[HTML][HTML] Effects of PGC-1α overexpression on the myogenic response during skeletal muscle regeneration

TA Washington, WS Haynie, ER Schrems… - Sports Medicine and …, 2022 - Elsevier
The ability of skeletal muscle to regenerate from injury is crucial for locomotion, metabolic
health, and quality of life. Peroxisome proliferator-activated receptor-γ coactivator-1α …

Characterization of the skeletal muscle arginine methylome in health and disease reveals remodeling in amyotrophic lateral sclerosis

J Wong, R Blazev, YK Ng, CA Goodman… - bioRxiv, 2024 - biorxiv.org
Arginine methylation is a protein post-translational modification important for the
development of skeletal muscle mass and function. Despite this, our understanding of the …