[HTML][HTML] Hyaluronic acid and chondroitin sulfate (meth) acrylate-based hydrogels for tissue engineering: Synthesis, characteristics and pre-clinical evaluation

CCL Schuurmans, M Mihajlovic, C Hiemstra, K Ito… - Biomaterials, 2021 - Elsevier
Hydrogels based on photocrosslinkable Hyaluronic Acid Methacrylate (HAMA) and
Chondroitin Sulfate Methacrylate (CSMA) are presently under investigation for tissue …

Chondroitin Sulfate: Emerging biomaterial for biopharmaceutical purpose and tissue engineering

R Sharma, K Kuche, P Thakor, V Bhavana… - Carbohydrate …, 2022 - Elsevier
Chondroitin Sulfate (CS) is an anionic hetero polysaccharide possessing anti-inflammatory,
antioxidant, antitumor, anticoagulant and antithrombogenic activities. It is biodegradable and …

Glycosaminoglycans: what remains to be deciphered?

S Perez, O Makshakova, J Angulo, E Bedini, A Bisio… - JACS Au, 2023 - ACS Publications
Glycosaminoglycans (GAGs) are complex polysaccharides exhibiting a vast structural
diversity and fulfilling various functions mediated by thousands of interactions in the …

Biotechnological advances in the synthesis of modified chondroitin towards novel biomedical applications

D Cimini, E Bedini, C Schiraldi - Biotechnology Advances, 2023 - Elsevier
Chondroitin sulfate (CS) is a well-known glycosaminoglycan present in a large variety of
animal tissues, with an outstanding structural heterogeneity mainly related to molecular …

Biosynthesis of non-animal chondroitin sulfate from methanol using genetically engineered Pichia pastoris

X Jin, W Zhang, Y Wang, J Sheng, R Xu, J Li, G Du… - Green …, 2021 - pubs.rsc.org
Chondroitin sulfate (CS) is widely applied in the medical, clinical, and nutraceutical fields.
However, all commercialized CS is extracted from animal tissues, which is associated with …

Advances and challenges in biotechnological production of chondroitin sulfate and its oligosaccharides

W Zhang, R Xu, J Chen, H Xiong, Y Wang… - International journal of …, 2023 - Elsevier
Chondroitin sulfate (CS) is a member of glycosaminoglycans (GAGs) and has critical
physiological functions. CS is widely applied in medical and clinical fields. Currently, the …

Chondroitin sulfate: are the purity and the structural features well assessed? A review on the analytical challenges

OF Restaino, C Schiraldi - Carbohydrate Polymers, 2022 - Elsevier
Animal origin chondroitin sulfate is employed as anti-inflammatory drug and food
supplement against anti-osteoarthritis, but also as antioxidant, antitumor, anticoagulant, and …

Microbial synthesis of glycosaminoglycans and their oligosaccharides

K Liu, L Guo, X Chen, L Liu, C Gao - Trends in Microbiology, 2023 - cell.com
Compared with chemical synthesis and tissue extraction methods, microbial synthesis of
glycosaminoglycans (GAGs) is attractive because of the advantages of eco-friendly …

Evaluation of novel biomaterials for cartilage regeneration based on gelatin methacryloyl interpenetrated with extractive chondroitin sulfate or unsulfated …

V Vassallo, A Tsianaka, N Alessio… - … Research Part A, 2022 - Wiley Online Library
Gelatin is widely proposed as scaffold for cartilage tissue regeneration due to its high
similarities to the extracellular matrix. However, poor mechanical properties and high …

[HTML][HTML] Heterologous production of chondroitin

MR Couto, JL Rodrigues, LR Rodrigues - Biotechnology Reports, 2022 - Elsevier
Chondroitin sulfate (CS) is a glycosaminoglycan with a broad range of applications being a
popular dietary supplement for osteoarthritis. Usually, CS is extracted from animal sources …